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TheAlkemist
Aug27-09, 11:03 PM
Is there any SCIENTIFIC evidence of the effect of ultrasound on chemical repair of DNA? As in, is there peer-reviewed research in this?

Thanks.

jim mcnamara
Aug28-09, 08:13 AM
This atricle shows that a chemotherapy-resistant ovarian cancer cell line ( because of DNA repair) becomes less resistant on exposure to ultrasound.

http://www.ingentaconnect.com/content/jws/uog/2009/00000033/00000003/art00017

Andy Resnick
Aug28-09, 08:49 AM
I couldn't read the whole article, just the abstract, but it doesn't make any sense. Ultrasound (MHz) has wavelengths in the millimeter range- how can targeted subcellular damage occur?

The abstract also did not mention the incident energy level, but I suspect it's much lower than occurs with UV damage.

TheAlkemist
Aug28-09, 01:34 PM
Thanks for the link Jim. I can't access the full article, but if you can, could you address Andy's question? I'm curious.
Thanks :)

Monique
Aug29-09, 10:11 AM
I couldn't read the whole article, just the abstract, but it doesn't make any sense. Ultrasound (MHz) has wavelengths in the millimeter range- how can targeted subcellular damage occur?

The abstract also did not mention the incident energy level, but I suspect it's much lower than occurs with UV damage. According to the introduction the ultrasound treatment leads to increased intracellular drug levels, I haven't read the study so I can't comment on the validity.