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The allergic response evolved to help expel parasites, and we think the worms have found a way of switching off the immune system in order to survive,” he said. “That’s why infected people have fewer allergic symptoms.
http://www.nytimes.com/2008/07/01/health/research/01prof.html?pagewanted=1&_r=1
There is plenty of evidence that hook worms in the gut have a profound effect on the immune system.
Would it be safe to infect oneself with such a worm, if you have allergies?