Insights Blog
-- Browse All Articles --
Physics Articles
Physics Tutorials
Physics Guides
Physics FAQ
Math Articles
Math Tutorials
Math Guides
Math FAQ
Education Articles
Education Guides
Bio/Chem Articles
Technology Guides
Computer Science Tutorials
Forums
Trending
Featured Threads
Log in
Register
What's new
Search
Search
Google search
: add "Physics Forums" to query
Search titles only
By:
Latest activity
Register
Menu
Log in
Register
Navigation
More options
Contact us
Close Menu
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Forums
Filament
Recent contents
View information
Top users
Description
The sliding filament theory explains the mechanism of muscle contraction based on muscle proteins that slide past each other to generate movement. According to the sliding filament theory, the myosin (thick) filaments of muscle fibers slide past the actin (thin) filaments during muscle contraction, while the two groups of filaments remain at relatively constant length.
It was independently introduced in 1954 by two research teams, one consisting of Andrew F. Huxley and Rolf Niedergerke from the University of Cambridge, and the other consisting of Hugh Huxley and Jean Hanson from the Massachusetts Institute of Technology. It was originally conceived by Hugh Huxley in 1953. Andrew Huxley and Niedergerke introduced it as a "very attractive" hypothesis.Before the 1950s there were several competing theories on muscle contraction, including electrical attraction, protein folding, and protein modification. The novel theory directly introduced a new concept called cross-bridge theory (classically swinging cross-bridge, now mostly referred to as (cross-bridge cycle) which explains the molecular mechanism of sliding filament. Cross-bridge theory states that actin and myosin form a protein complex (classically called actomyosin) by attachment of myosin head on the actin filament, thereby forming a sort of cross-bridge between the two filaments. The sliding filament theory is a widely accepted explanation of the mechanism that underlies muscle contraction.
View More On Wikipedia.org
Forums
Back
Top