Can microbes combat neurodegeneration? - Apparently YES

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In summary, recent studies have shown that the gut microbiome may play a significant role in ALS symptoms, as evidenced by the production of nicotinamide by gut bacteria which has been found to improve motor abilities and spinal cord gene expression in mice. Further research is needed to explore the potential impact of the gut microbiome on ALS in humans.
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Tom.G
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At least for ALS symptoms in mice; and some suspicions in humans based on sequencing the gut microbiome of patients vs. healthy family members in the same household.

They found that the gut bugs produced nicotinamide which "...substantially improved motor abilities and spinal cord gene expression in [the] mice."
https://science.sciencemag.org/content/373/6551/172.long

and other articles at
https://pubmed.ncbi.nlm.nih.gov/34244406/
 
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That's really interesting! It seems like the gut microbiome could have a huge impact on ALS symptoms, not just in mice but potentially in humans as well. I'm looking forward to more research on this topic, and seeing if it can make a difference in the lives of those who suffer from ALS.
 

FAQ: Can microbes combat neurodegeneration? - Apparently YES

How do microbes combat neurodegeneration?

Microbes can combat neurodegeneration through various mechanisms such as producing anti-inflammatory compounds, promoting the growth of nerve cells, and enhancing the immune system's response to neurodegenerative diseases.

What types of microbes are effective in combating neurodegeneration?

Various types of microbes have shown potential in combating neurodegeneration, including probiotics, gut bacteria, and certain viruses. However, more research is needed to determine which specific strains or species are most effective.

Can microbes prevent neurodegenerative diseases?

While there is evidence that microbes can slow down the progression of neurodegenerative diseases, it is not yet clear if they can completely prevent these diseases. More research is needed to fully understand the role of microbes in preventing neurodegeneration.

Are there any risks associated with using microbes to combat neurodegeneration?

Like any medical treatment, there may be potential risks associated with using microbes to combat neurodegeneration. These risks can include allergic reactions, interactions with other medications, and the potential for the microbes to become resistant to treatment.

Can microbes combat neurodegeneration in all individuals?

The effectiveness of microbes in combating neurodegeneration may vary among individuals. Factors such as genetics, lifestyle, and the specific type of neurodegenerative disease may impact the effectiveness of microbial treatment. Further research is needed to determine the best approach for each individual.

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