Injecting Large volume of Nanoparticles

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In summary, the interaction of nanoparticles with the human immune system can vary depending on the type of particle. The immune system has specific rules and reactions to certain substances, but if nanoparticles are designed to mimic the body's own cells, they may be accepted. This is similar to how cancer cells evade the immune system by appearing more like the body's own cells.
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ceaweaw
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Supposing that our body is injected with a large volume of nanoparticles carrying some specific agents to filter out our blood, I don't understand how our body HIS (human immune system) can ignore its main task to accept the agents as friends, especially after these particles succeed, where will they go ?

http://pubs.acs.org/doi/abs/10.1021/bm900266r
 
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The interaction of nanoparticles with any biological system is going to be different depending on the particle in question. A liposome isn't going to be reacted to the same way as a carbon nanotube for instance.
 
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hmm well the immune system has specific inclinations and rules it follows. For example it won't ignore poly saccharides on anything, often associated with bacteria cell walls, and also unfortunately found in some vaccines causing allergical reactions. It doesn't like antigens with specific patterns found with viruses. But if you made molecules that are more similar to the body's own cell surface proteins, it might work.

This is how cancer evades the immune system. Even when the immune system go after cancer cells it's the non specific WBCs and not your T and B cells that do the job.
 

FAQ: Injecting Large volume of Nanoparticles

What is the purpose of injecting large volumes of nanoparticles?

The purpose of injecting large volumes of nanoparticles is to introduce a high concentration of these tiny particles into a specific area of the body. This allows for targeted delivery of drugs or other therapeutic agents, as well as imaging and diagnostic purposes.

What are the potential risks associated with injecting large volumes of nanoparticles?

The potential risks of injecting large volumes of nanoparticles include local inflammation or tissue damage, as well as systemic effects such as immune responses or toxicity. These risks can vary depending on the type and properties of the nanoparticles being injected.

How are nanoparticles typically injected in large volumes?

Nanoparticles can be injected in large volumes through various methods such as intravenous, intramuscular, subcutaneous, or intra-articular injections. The specific method used depends on the intended target and purpose of the injection.

What factors determine the success and effectiveness of injecting large volumes of nanoparticles?

The success and effectiveness of injecting large volumes of nanoparticles depend on factors such as the size, shape, surface properties, and concentration of the nanoparticles, as well as the method and location of injection. Additionally, the body's response to the injected nanoparticles can also affect their effectiveness.

What are some potential applications of injecting large volumes of nanoparticles?

Injecting large volumes of nanoparticles has a wide range of potential applications, including targeted drug delivery for cancer treatment, imaging and diagnosis of diseases, as well as regenerative medicine and tissue engineering. It can also be used for environmental remediation and industrial processes.

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