Location of 5' & 3' UTRs - Nucleotide Sequence 1-1430

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In summary, 5' and 3' UTRs are non-coding regions found at the beginning and end of a messenger RNA molecule. They play important roles in regulating gene expression by containing regulatory sequences and signals for mRNA stability and transport. The length of these regions can vary depending on the specific nucleotide sequence and it is important to know their location to understand gene regulation and to identify potential drug targets. The location of 5' and 3' UTRs can also vary between different organisms and genes within the same organism, which can affect gene expression and protein function.
  • #1
hivesaeed4
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Suppose we have a sequence of nucleotides 1 - 1430.

The gene is from 606 - 1430.
The mRNA is from 606-1170. So is the exon (i.e. its 606-1170).
The CDS is from 990-1170.

What would be the location of the 5' and 3' UTR's?

I think the 5' UTR would be 606-990 and the 3' UTR would be 1170-1430 respectively.

Correct?
 
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  • #2
The 3' UTR is part of the mRNA, so 1170-1430 cannot be the 3'UTR if the mRNA ends at nucleotide 1170.
 

FAQ: Location of 5' & 3' UTRs - Nucleotide Sequence 1-1430

What are 5' and 3' UTRs?

5' and 3' UTRs stand for the 5' and 3' untranslated regions of a nucleotide sequence. These regions are found at the beginning and end of a messenger RNA (mRNA) molecule and do not code for proteins.

What is the function of the 5' and 3' UTRs?

The 5' and 3' UTRs play important roles in regulating gene expression. They contain regulatory sequences that control the translation of mRNA into protein, as well as signals for mRNA stability and transport.

How long are the 5' and 3' UTRs in the nucleotide sequence 1-1430?

The length of the 5' and 3' UTRs can vary depending on the specific nucleotide sequence. In this case, the 5' UTR is likely 1-1430 nucleotides long, while the 3' UTR is the remaining nucleotides until the end of the sequence. The exact length of each UTR can be determined by analyzing the sequence.

Why is it important to know the location of 5' and 3' UTRs in a nucleotide sequence?

By knowing the location of 5' and 3' UTRs, researchers can better understand the regulatory mechanisms that control gene expression. This information can also be used to identify potential drug targets, as well as to design experiments to study the function of specific UTR sequences.

Can the location of 5' and 3' UTRs change in different organisms?

Yes, the location of 5' and 3' UTRs can vary between different organisms and even within different genes in the same organism. This variation is due to evolutionary changes and can affect gene expression and protein function. Therefore, it is important to study the specific UTR sequences in the organism of interest.

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