Protease cleavage is a process in which enzymes called proteases break down proteins by cutting the peptide bonds that hold them together. This process is important in many biological processes, such as digestion and protein turnover.
The N-terminal and C-terminal refer to the two ends of a protein chain. The N-terminal is the starting point of the protein chain, while the C-terminal is the end point. The position of protease cleavage can have different effects on the function and structure of a protein.
S102 is a specific amino acid residue (serine) at position 102 in a protein chain. It is important in protease cleavage as it is the site where the protease enzyme will cut the protein chain.
No, protease cleavage can occur at various positions along the protein chain, depending on the specific protease enzyme and its target amino acid sequence. Some proteases may only cleave at the N-terminal or C-terminal, while others may cleave at multiple sites.
The position of protease cleavage can have various effects on protein function. For example, cleavage at the N-terminal may result in a loss of function, while cleavage at the C-terminal may lead to a change in protein structure. It can also affect the activity, stability, and localization of a protein.