Interesting developments; I'm not sure how controversial this is...
https://www.cnn.com/2023/11/16/health/uk-casgevy-approval-crispr-gene-editing-sickle-cell-scn/index.html
The New England Journal of Medicine published two papers showing data for successful treatment of a handful of patients with sickle cell disease or β- thalassemia using gene therapy techniques. Both teams used the strategy of inhibiting the BCL11a transcription factor in blood cells, which...
Encouraging news that the technology can potentially cure a number of genetic disorders
https://www.npr.org/sections/health-shots/2019/11/19/780510277/gene-edited-supercells-make-progress-in-fight-against-sickle-cell-disease
Over the past half decade, researchers have envisioned the https://www.physicsforums.com/insights/dont-fear-https://www.physicsforums.com/insights/dont-fear-crispr-new-gene-editing-technologies-wont-lead-designer-babies/-new-gene-editing-technologies-wont-lead-designer-babies/system as a way to...
crispr-as-gene-editing-human-trials-get-underway?utm_source=twitter.com&utm_medium=social&utm_campaign=npr&utm_term=nprnews&utm_content=20190416]First U.S. Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway[/url]
The study takes immune cells out of the patient, modifies them...
https://www.physicsforums.com/insights/dont-fear-https://www.physicsforums.com/insights/dont-fear-crispr-new-gene-editing-technologies-wont-lead-designer-babies/-new-gene-editing-technologies-wont-lead-designer-babies/ is a newly developed tool that allows researchers to easily make changes to...
https://apnews.com/4997bb7aa36c45449b488e19ac83e86d
As detailed in the AP news story, most scientists believe the work to be unethical as the safety of the CRISPR gene editing technique used has not yet been fully established.
See also...
Mosquitoes are responsible for spreading a number of human diseases (including malaria, Dengue fever, and Zika virus), and account for nearly half a million deaths per year worldwide. For many years, scientists have been investigating technologies that could help control or even eliminate...
@Ygggdrasil is far more qualified to comment on this than I am, but it seems like a good idea to raise the issue. Published today July 16, 2018 Letter in Nature Biotechnology:
https://www.nature.com/articles/Nbt.4192
M. Kosicki, K. Tomberg & A Bradley
Abstract:
In plain English this says...
Why is gold un-reactive enough to be used as nanoparticles?
Why do cells preform endocytosis upon detection of the gold delivery system? What are the chemical receptors active?
Why is does it cause less genetic damage than doing it virally?
Is this system partly designed to change the DNA of...
https://www.physicsforums.com/insights/dont-fear-https://www.physicsforums.com/insights/dont-fear-crispr-new-gene-editing-technologies-wont-lead-designer-babies/-new-gene-editing-technologies-wont-lead-designer-babies/provides scientists with an easy way to introduce targeted genetic changes to...
U.S. Doctors Plan to Treat Cancer Patients Using CRISPR
https://www.technologyreview.com/s/609999/us-doctors-plan-to-treat-cancer-patients-using-crispr/
CRISPR is often used to switch out a length of DNA for a different piece of sequence, which can change several base pairs at once.
crispr-derived-base-editors-surgically-alter-dna-or-rna-offering-new-ways-fix?utm_campaign=news_daily_2017-10-25&et_rid=33537079&et_cid=1624006']Here is a Science...
Egli, D. et al. Preprint at http://www.biorxiv.org/content/early/2017/08/28/181255 (2017).
A critique of: doi:10.1038/nature.2017.22382 (dated Aug 2)
Here is the more news science version of the CRISPR study:
https://www.nature.com/news/crispr-fixes-disease-gene-in-viable-human-embryos-1.22382...
Hello guy, been a while since I was here, recently I've been studying biology and we had a brief explanation on what cripsr cas9 is.
My teacher does not have answers to the questions I need so I will ask them here and sorry If there is misspelling here and there, I am on my phone.
First of...
http://www.nature.com/news/lights-camera-crispr-biologists-use-gene-editing-to-store-movies-in-dna-1.22288
"The technical achievement, reported on 12 July in Nature1, is a step towards creating cellular recording systems that are capable of encoding a series of events, says Seth Shipman, a...
A major impediment to curing patients with HIV is the fact that the virus integrates its DNA into the genome of the cells it infects. While antiretroviral drugs and therapies can prevent infection of new cells and kill cells that are actively producing virus, a "latent reservoir" remains that...
Right I've read all about CRISPR but I can't help to think if such a possibility exists. As far as I know the only way to cause such changes is by modifying cells at the embryo stage. But if crispr can help grow a missing limb or create structural changes at adult stage it does sound like a...
Ygggdrasil submitted a new PF Insights post
https://www.physicsforums.com/insights/dont-fear-https://www.physicsforums.com/insights/dont-fear-crispr-new-gene-editing-technologies-wont-lead-designer-babies/-new-gene-editing-technologies-wont-lead-designer-babies/...