insulin Definition and 19 Threads

In your 2 diabetes insulin secretion is present, but it is ineffective. It means that the circulating insulin is unable to push all the glucose into cells. They call it insulin resistance. But at the same time, if synthetic insulin is injected or insulin-secreting drugs are given, they seem to...

Insulin's role in glucose metabolism by translocating GLUT-4 proteins into the plasma membrane (thereby regulating the uptake of glucose), in the adipose and skeletal muscle cells, is rather well known. And in the liver, insulin aids to regulate gluconeogenesis and promoting glycogen synthesis...

Type-2 diabetes patients generally display higher levels of glucose circulating in their blood. While type-1 is considered a lack of insulin disease, in type-2 it is considered that insulin may be present, but it is not working properly. It is called Insulin-resistance. Most of the drugs for...

We know that insulin and Glucagon are considered antagonistic hormones as they help us to maintain the homeostatic glucose level for our cells. When the concentration of blood glucose rises (after eating, for example), beta cells of the pancreas secrete insulin into the blood. Insulin helps to...

Hi Guys I have metabolic syndrome, amongst other things. A friend has all the signs - sleep apnia, low testosterone, high AST, high ferritin, high blood pressure, horrid cholesterol, belly fat etc. Yet despite test after test he does not have insulin resistance. Me I am way insulin...

We know that type 2 diabetes is caused by insulin insufficiency/resistance. Normally Insulin causes GLUT4 in the liver and muscle/adipose cells to surface at their cell membrane, to facilitate the transport of glucose from the circulating blood. Type2DM lacks this action and hence glucose...

Well, I am confused on insulin resistance and cellular signaling. Know... Below is my understand: Insulin resistance happens either when the paceraes does not produce enough of the protein insulin and another way resistance occurs is when the receptor is not functioning properly. Are there...

I have just read that genetically modified e. coli can synthesize human insulin. But I wonder. Human (eucaryotic) genes have all kinds of introns, regulators, starting sequences etc. Bacteria don't have all of those. How can a procaryota produce an eucaryotic peptide? Has the insulin gene been...

During fight-or-flight situations, alpha 2 receptors ( which are inhibitory receptors ) of the pancreatic beta cells are stimulated, and as a result there's decreased insulin production. While it benefits the body by producing increased blood sugar level, I don't understand why Insulin doesn't...

Can high insulin make you fat directly? I thought this was a very interesting study because it seems to question the usual relationship between insulin levels, insulin resistance and obesity: Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Production...

I'm reading an article about glucose dynamics and there were two terms I wasn't sure about. I'm guessing insulin sensitivity is how much glucose is absorbed by a certain amount of insulin, but what is glucose effectiveness? Any help is appreciated.

I've been recently reading up on diabetes and there's some questions I can't find the answers to so if anyone here know please help Are insulin needles used for type 2 diabetes? -I keep hearing ppl saying that they are but isn't type 2 when the body doesn't respond to insulin? Type 2...

What are the characteristics of insulin produced by the enzyme Genetic Engineering ? Is identical of the human insulin ?

I'm what you would, in the bodybuilding world, call a hardgainer. No matter what I do I can't gain weight. I used to eat lots of carbs on a 4000 Calorie diet and nothing happened as far as weight gain. I would just get frequent urination and a fruitish odor in the back of my mouth and would...

Does anyone know how insulin is produced nowadays? I know that bacteria get a human gene which codes for the production of insulin, but I'd like to get some more in-depth information because we have to make a folder at school.

In my assay of 50uL of 125-I-insulin I have 20,000 cpm at the expiry date. The half life of 125-I-Insulin is 60 days. So how can I calculate how many counts a 50uL sample of 125-I-labelled insulin would contained at 4 months past the expiry date? cheers

The presence of insulin increases the activity of the GLUT4 glucose transporters and not the actual number of the transporters. In a freeze fracture, it appeared that the GLUT4s moved from the internal membrane into the plasma membrane. I am asked to deduce the mechanism by which glucose...

I have a question that says: Which of the following hormons are produced in the kidneys: Insulin, adrenaline, growthhormon, EPO or thyroxine ? Thanks again :D

I'm trying to understand what a person said (from ahttp://forums.whirlpool.net.au/forum-replies.cfm?t=162168&p=4 . Later on, he goes to say that without insulin, eating excess fat would not cause you to get fat (near the bottom of the page). I'm confused... I'm sure insulin regulated the...