- #1
dspampi
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I was able to do the first part of this problem but unsure how to approach this:
Mendel, revisited: Mendel’s peas had either purple or white flowers; flower color is due to a single gene, for which the purple allele (A) is dominant to the white allele (a). We cross two pure-breeding lines (one purple and one white) to produce the F1 hybrid. We self the F1 and choose an F2 seed at random. We grow and self the F2 and choose two F3 seeds at random. Consider the following events A1 = {F3 number 1 has purple flowers} and A2 = {F3 number 2 has purple flowers}.
(b) Are A1 and A2 conditionally independent, given F2? In other words, is Pr(A1 and A2| F2) = Pr(A1|F2) × Pr(A2| F2)?
Say for instance if F2 where heterozygote (Aa); ...AA means homozygote (purple) and aa (white)
I know:
P(A1 and A2) = P(A1 and A2 | Aa) P(Aa) + P(A1 and A2 | AA) P(AA) + P(A1 and A2 | aa) P(aa)
=(3/4)^2*(1/2)+1*(1/4)+0*(1/2)= 0.53
P(A1) = P(A2) = P(A1 | Aa) P(Aa) + P(A1 | AA) P(AA) + P(A1 | aa) P(aa)
= (3/4)*(1/2) + 1*(1/4) + 0*(1/4) = 0.625
Mendel, revisited: Mendel’s peas had either purple or white flowers; flower color is due to a single gene, for which the purple allele (A) is dominant to the white allele (a). We cross two pure-breeding lines (one purple and one white) to produce the F1 hybrid. We self the F1 and choose an F2 seed at random. We grow and self the F2 and choose two F3 seeds at random. Consider the following events A1 = {F3 number 1 has purple flowers} and A2 = {F3 number 2 has purple flowers}.
(b) Are A1 and A2 conditionally independent, given F2? In other words, is Pr(A1 and A2| F2) = Pr(A1|F2) × Pr(A2| F2)?
Say for instance if F2 where heterozygote (Aa); ...AA means homozygote (purple) and aa (white)
I know:
P(A1 and A2) = P(A1 and A2 | Aa) P(Aa) + P(A1 and A2 | AA) P(AA) + P(A1 and A2 | aa) P(aa)
=(3/4)^2*(1/2)+1*(1/4)+0*(1/2)= 0.53
P(A1) = P(A2) = P(A1 | Aa) P(Aa) + P(A1 | AA) P(AA) + P(A1 | aa) P(aa)
= (3/4)*(1/2) + 1*(1/4) + 0*(1/4) = 0.625