Blood groups and transfusions .

In summary, blood groups and transfusions involve the risk of agglutination if the wrong blood type is transfused. However, AB individuals can receive A blood because their blood contains no antibodies. Although A blood may contain anti-B antibodies, it may not always cause a significant immune response in AB individuals. Therefore, AB individuals are still considered universal recipients, but they may prefer to receive blood from another AB donor to minimize the risk of agglutination.
  • #1
Cheman
235
1
Blood groups and transfusions...

I have learned that when you transfuse the wrong blood to a recipient whose antibodies work against the donated blood that agglutination occurs. eg - if you transfuse A blood to a B person, since the B person will possesses anti-A antibodies which will cause agglutination, but an AB person can receive A blood because their blood contains no antibodies.

But surely the donated A blood would contain some anti-B antibodies which would cause agglutination of the red blood cells in the AB person? Why does this not happen? ie - we still call the AB a universal recipient.

Thanks.
 
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  • #2
Cheman said:
But surely the donated A blood would contain some anti-B antibodies which would cause agglutination of the red blood cells in the AB person? Why does this not happen? ie - we still call the AB a universal recipient.

It does happen on some occasion but people of group AB will preferentially receive blood from an AB person rather than anyone else.

You also have to note the amount of anti-B antibodies in the transfused blood might be not sufficient to cause a significant immune responce in certain individuals.
 
  • #3
Please could people elaborate?
 

Related to Blood groups and transfusions .

What are blood groups and why are they important?

Blood groups are classifications of blood based on the presence or absence of certain antigens on the surface of red blood cells. They are important because they determine compatibility for blood transfusions and can also affect an individual's susceptibility to certain diseases.

How many blood groups are there?

There are four main blood groups: A, B, AB, and O. These groups are further categorized into positive (+) or negative (-) based on the presence of the Rhesus (Rh) factor.

What is the universal blood donor and recipient?

O negative (O-) is considered the universal blood donor as their blood can be transfused to individuals with any blood type. AB positive (AB+) is considered the universal blood recipient as they can receive blood from any blood type.

Why is cross-matching important in blood transfusions?

Cross-matching is important to ensure compatibility between the donor's blood and the recipient's blood. This is done by mixing a small sample of the donor's blood with the recipient's blood and observing for any reactions. If there is a mismatch, it could lead to a potentially life-threatening immune response in the recipient's body.

Can blood groups change over time?

No, blood groups do not change over time. They are determined by genetics and remain the same throughout a person's life. However, certain medical conditions or treatments may alter the antigens on red blood cells, causing a temporary change in blood type.

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