- #1
cobby174
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So there I was thinking, if the mother was Rhesus Negative and she had a Rhesus positive baby, her antibodies would cross the placenta and attack the Rhesus positive baby's red blood cells (assuming second child).
Then I thought, well, what if the mother was Rhesus positive, and the baby was Rhesus negative?
Well...firstly, Rhesus positive (Rh+) is dominant, yes? It causes the expression of the important "D" antigen on the surface of RBC. Therefore, a Rhesus positive mother and a Rhesus negative father would give a Rhesus positive baby. Therefore, we can conclude that the mother can never be Rhesus positive while the foetus/(baby) was Rhesus negative or at least...this scenario is unlikely?!
But wait...
What if, we took a Rh- mother's egg, and a Rh- father's sperm, fertilised it and through IVF placed it in a Rh+ SURROGATE mother? What effects would occur?!
Would nothing occur because the foetus does not produce antibodies at all?
- Cobby
P.S. Yes I just wanted to let you know I went through the thought process...took a while to get to the question :)
Then I thought, well, what if the mother was Rhesus positive, and the baby was Rhesus negative?
Well...firstly, Rhesus positive (Rh+) is dominant, yes? It causes the expression of the important "D" antigen on the surface of RBC. Therefore, a Rhesus positive mother and a Rhesus negative father would give a Rhesus positive baby. Therefore, we can conclude that the mother can never be Rhesus positive while the foetus/(baby) was Rhesus negative or at least...this scenario is unlikely?!
But wait...
What if, we took a Rh- mother's egg, and a Rh- father's sperm, fertilised it and through IVF placed it in a Rh+ SURROGATE mother? What effects would occur?!
Would nothing occur because the foetus does not produce antibodies at all?
- Cobby
P.S. Yes I just wanted to let you know I went through the thought process...took a while to get to the question :)