Does Matching FTIR Peaks Indicate Sample Purity?

In summary, the conversation discussed the results of an FTIR spectrum collected on a sample and a standard. It was noted that all peaks in the spectrum matched, but the standard had several peaks that absorbed more light than the sample. This could indicate that the sample is not as pure as the standard, potentially due to the presence of an IR inactive salt or other impurities. Further testing may be required to confirm this.
  • #1
ldc3
14
0
I collected FTIR spectrum (using an ATR stage) on a sample and a standard and noticed the following: (1) all the peaks in the spectrum matched, and (2) the standard had several peaks that absorbed more light than the sample (see 2nd page on attachment). Does this mean that the sample is not as pure as the standard (i.e. an IR inactive salt is mixed with the sample).
 

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  • #2
Yes, it is possible that the sample is not as pure as the standard if the standard has several peaks that absorb more light than the sample. This could be indicative of an IR inactive salt being mixed with the sample, or it could be due to other impurities present in the sample. To confirm this, additional testing (e.g. HPLC, GC-MS) may be necessary.
 

Related to Does Matching FTIR Peaks Indicate Sample Purity?

1. What is an FTIR spectrum and how is it obtained?

An FTIR (Fourier Transform Infrared) spectrum is a graph that shows the absorption of infrared radiation by a sample. It is obtained by passing infrared light through a sample and measuring the amount of light absorbed at different wavelengths using a Fourier transform infrared (FTIR) spectrometer.

2. What information can be obtained from an FTIR spectrum?

An FTIR spectrum can provide information about the functional groups present in a sample, as well as the chemical bonds and molecular structure. It can also be used to identify specific compounds or substances present in a sample.

3. How do you interpret an FTIR spectrum?

Interpretation of an FTIR spectrum involves analyzing the peaks and valleys on the graph, which correspond to the absorption of infrared light at different wavelengths. The location and intensity of these peaks can provide information about the type and number of functional groups present in the sample.

4. What factors can affect the interpretation of an FTIR spectrum?

The interpretation of an FTIR spectrum can be affected by a number of factors, including the sample preparation method, the type of sample (solid, liquid, or gas), and the instrument settings. It is also important to consider the background noise and baseline correction when interpreting the spectrum.

5. How is an FTIR spectrum used in different industries or fields?

FTIR spectroscopy is widely used in various industries and fields, such as pharmaceuticals, food and beverage, environmental science, and forensics. It can be used for quality control, product development, and identification of unknown substances. In research, FTIR is used for chemical analysis, material characterization, and studying chemical reactions.

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