How Accurate is a Positive Disease Test Result?

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In summary, the probability of having a disease with a positive test result depends on the prevalence of the disease in the population and the accuracy of the test. False positives and false negatives can significantly impact the probability, with a false positive decreasing it and a false negative increasing it. Other factors such as test sensitivity and specificity, age and health status, and risk factors can also influence the probability. This probability can change over time as new information becomes available, and it can help inform treatment decisions but should not be the sole factor considered.
  • #1
Jameson
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A blood test indicates the presence of a particular disease 95% of the time when the disease is actually present. The same test indicates the presence of the disease 0.5% of the time when the disease is not present. One percent of the population actually has the disease. Calculate the probability that a person has the disease given that the test indicates the presence of the disease.

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  • #2
Congratulations to the following members for their correct solution:

1) Sudharaka
2) veronica1999
3) BAdhi

Solution:

[sp] This is a conditional probability problem.

Let B represent the probability that the blood test indicates the presence of the disease and D represent that a person has the disease. We want to find \(\displaystyle P(D|B)\).

By definition of conditional probability \(\displaystyle P(D|B) = \frac{P(D \cap B)}{P(B)}\). From the information given in the problem we know that \(\displaystyle P(D \cap B) = (.01)(.95)=.0095\)

Now to find the probability of B we must consider two cases: the blood test indicates the presence of the disease and the person has the disease (1) and the blood test indicates the presence of the disease and the person does not have the disease (2).

(1) \(\displaystyle (.95)(.01)=.0095\) (The test was positive and the person has it)
(2) \(\displaystyle (.005)(.99)=.00495\) (The was positive, meaning the test was incorrect, and the person does not have it)

\(\displaystyle P(B) = (1)+(2) = .0095+.00495=.01445\)

Our final answer is \(\displaystyle P(D|B) = \frac{P(D \cap B)}{P(B)}=\frac{.0095}{.01445}=.6574\)

So even though this test is 95% accurate and only 1% of the population has the disease we arrive a surprisingly low percent of 65.7. This is a good example of how conditional probability can be used to show how wrong our intuitions are about some things :)[/sp]
 

Related to How Accurate is a Positive Disease Test Result?

1. What is the probability of having a disease if you receive a positive test result?

The probability of having a disease with a positive test result depends on the prevalence of the disease in the population and the accuracy of the test. It is important to consider both factors when interpreting the results.

2. How do false positives and false negatives affect the probability of disease with a positive test result?

False positives and false negatives can significantly impact the probability of disease with a positive test result. A false positive (when the test result is positive but the person does not actually have the disease) decreases the probability, while a false negative (when the test result is negative but the person does have the disease) increases the probability.

3. Are there any other factors that can influence the probability of disease with a positive test result?

Yes, there are other factors that can influence the probability of disease with a positive test result, such as the sensitivity and specificity of the test, the age and health status of the individual, and any potential risk factors for the disease.

4. Can the probability of disease with a positive test result change over time?

Yes, the probability of disease with a positive test result can change over time as new information and data become available. It is important to regularly assess and update the probability based on the latest evidence.

5. How can we use the probability of disease with a positive test result to make informed decisions about treatment?

The probability of disease with a positive test result can help inform treatment decisions by providing an estimate of the likelihood that an individual has the disease. However, it should not be the only factor considered and should be interpreted in conjunction with other clinical and diagnostic information.

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