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Hornbein
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Nicely done. Supercomputer?
They say the animation is real time but wouldn't the real thing be much quicker?
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Why's that?Hornbein said:They say the animation is real time but wouldn't the real thing be much quicker?
Because molecules are minuscule. Things happen much faster way down there.Drakkith said:Why's that?
Without a clear indication of how fast things are happening in the video I can't say anything either way. The speed looked plausible to my mostly untrained eye but that doesn't mean much.Hornbein said:Because molecules are minuscule. Things happen much faster way down there.
At one million times magnification that's equivalent to 20 years for a gene transcription. I guess that's the cellular equivalent of building a cathedral. Depending so heavily on random thermal motion slows things down. Two years for protein translation, no wonder they need so many copies of everything in order to get anything done.Frabjous said:If I look at this, it says that transcription takes about 10min/gene and that protein translation takes around 1min/protein (for mammalian cell lines)
https://www.cell.com/cell/pdf/S0092-8674(16)30208-2.pdf
What does magnification have to do with the time it takes for transcription?Hornbein said:At one million times magnification that's equivalent to 20 years for a gene transcription.
It is a measure of how small the things in question actually are. One million times smaller than what we see on the screen. Things are a million times closer together and weigh a quintillion times less than things of the size we see on the screen. So I'd expect construction to go a million times faster. If it were purposeful I suppose it would. So depending so heavily on random thermal motion slows things down a million times. That's the rough idea.Drakkith said:What does magnification have to do with the time it takes for transcription?
That's not how it works. Magnification has nothing to do with how fast something takes.Hornbein said:It is a measure of how small the things in question actually are. One million times smaller than what we see on the screen. Things are a million times closer together and weigh a quintillion times less than things of the size we see on the screen. So I'd expect construction to go a million times faster.
Oh come on. If two things are a million times closer together, they can be assembled much more quickly. I'm not going to respond to this bald assertion again.Drakkith said:That's not how it works. Magnification has nothing to do with how fast something takes.
What? Magnification is an optical effect, not a physical one. If I zoom in on some ants with my camera they don't suddenly slow down because they are bigger.Hornbein said:Oh come on. If two things are a million times closer together, they can be assembled much more quickly. I'm not going to respond to this bald assertion again.
Hornbein said:
Nicely done. Supercomputer?
They say the animation is real time but wouldn't the real thing be much quicker?
Yep, Brownian motion all right. Colors added just to help distinguish what's what.pinball1970 said:I liked the video, I have no idea how accurate it is in terms of speed.
Gene transcription looks pretty quick, see the molecules whizzing past in the cytoplasm?
I was wondering why everything was vibrating like that then remembered Brownian motion, I suppose that is it?
I assume all the colours are added.
I loved the sounds, who noticed the Bee sound during epigenetic tagging!
Separation is not magnification - length is the relevant unit.Hornbein said:If two things are a million times closer together
In the context of DNA animation, "real-time" refers to the ability to visualize and simulate biological processes as they occur, without significant delays or time lags. This means that the animation reflects the actual timing and sequence of molecular events, allowing researchers to observe dynamic interactions and changes in DNA structures as they happen in living cells.
DNA animation is typically created using computational models and simulations that incorporate data from experimental observations. Researchers use software tools to visualize molecular structures and dynamics, often employing techniques such as molecular dynamics simulations, which calculate the movements of atoms and molecules over time based on physical principles.
The limitations of real-time DNA animations include computational constraints, where the complexity of molecular interactions may exceed current processing capabilities. Additionally, simplifications may be necessary to make the animation comprehensible, which can lead to a loss of detail or accuracy in representing the actual biological processes. Furthermore, real-time simulations may not capture all variables influencing DNA behavior under varying conditions.
Yes, real-time DNA animations have several practical applications, including educational purposes, where they help students and researchers visualize complex biological processes. They are also valuable in drug design, allowing scientists to observe how potential drugs interact with DNA and other biomolecules. Additionally, these animations can aid in understanding genetic mutations and their implications for diseases.
Researchers can ensure the accuracy of DNA animations by validating their models against experimental data from laboratory studies. This includes using high-resolution imaging techniques, such as cryo-electron microscopy or X-ray crystallography, to obtain precise structural information. Continuous refinement of simulation parameters and algorithms based on new findings also contributes to the reliability of the animations.