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loseyourname
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Manchot said:Just FYI, some of my statistics came from http://www.karlloren.com/Diabetes/p17.htm, a copy of a New England Journal of Medicine article on this issue.
Thanks. I'll take a look at that and try my best to figure out what the breakdown is and where they're getting the numbers from.
Something that I noticed that I think is worth mentioning right off the bat is the comment the author makes about the riskiness of being in the pharmaceutical industry. The very large companies themselves don't risk much collectively, since they have such a huge number of products on the market and in development all the time. As such, these companies make a safe investment for shareholders and the CEO is probably fairly secure. The careers of lower-level executives, the R&D division chairs and such, is not nearly as secure, however. If one man oversees two or three failed projects consecutively, even though the company overall might be doing quite well, his department just lost hundreds of millions (perhaps even billions) of dollars and is going to be cut. Many doctors also stake their reputation on one or two drugs that they develop, and if these fail, their careers can be ruined. Even if the industry is doing quite well, it isn't all hunky dory for everyone.
Note: While all of the above is probably pretty obvious and mostly not relevant, I just wanted to ensure that nobody gets the idea that there is any such thing as a sure bet in business, even in industries as wildly profitable as pharmaceuticals. The researchers themselves are quite well paid and secure, but the men who attempt to get fabulously rich in the higher positions quite often do fail. I get the impression that discussions of business tend to focus on nameless, faceless corporations and forget that these are populated by individuals.
The generic market is much less profitable than the new drug market. The generic market is almost perfectly competitive: there's not much money to be made there, and lulls in demand can force companies out of business. On the other hand, if you develop a new, innovative drug, then you can have a temporary monopoly.
That's the thing, though. If you take away the monopolies by allowing imports that circumvent the patents, there is no more incentive to innovate. No matter how high their profits may be right now, the patents (along with doctor recommendations) are the sole source of those profits. Take those away and you take away the profitability.
Don't get me wrong here. I'm not making a direct comment on whether or not we should allow any importation. To be honest, I'm not that knowledgeable about foreign pharmaceutical companies and what kinds of laws and approval processes they go through. I'm just trying to say that the current embargo on imports isn't just about maintaining profits for powerful lobbyists. There are two other issues that are very important: 1) Maintaining the patent monopolies that make innovation worthwhile in the first place. If the imports are being manufactured by the same company or manufactured after the patent has run out for the domestic drug, go ahead and allow it. 2) If we allowed US citizens to buy drugs that were not FDA-approved, why have an FDA approval process for drugs in the first place? Of course, people do have this option already with herbal medicines, which are not regulated. I'm sure many work quite well, but naturally there are many that make sham claims and intentionally rip off desperate people.
According to Frontline, clinical trials make up 75% of development costs, so one would assume that that is counted as part of R & D costs. Unfortunately, there's no possible way to get an exact breakdown, because the drug companies have a disincentive to publish that information.
Well, I could ask my old contact (who is semi-retired on permanent disability and has no incentive to lie), but I haven't talked to him in years.
Edit: By the way, I felt I should add that even though I may know people involved in the industry, obviously they can't actually reveal trade secrets or financial records to me. Just in case anybody is getting the mistaken impression that I'm somehow in the know - I'm not.
I'm not suggesting that price controls be implemented. I'm not even suggesting that patents be removed, only that they be enforced correctly.
I can't disagree with you there. I only present the case for the pharmaceutical industry because it seems like everyone else around here is so hellbent on presenting the case against it. The forum requires balance. You've been very fair in your assessment, though. I'm quite impressed. You rarely see fairness in a political discussion.
As it stands, the industry is always trying to weasel its way around patent law. For example, when one drug's patent is about to expire, they'll often package it together with another one, and get the combo patented. Then, unsuprisingly, they take the original off the market and rebrand it. Also, the USPTO needs to be far less lenient when it comes to the "me-too" drugs. (This doesn't just apply to the drug market: the patent office is far too lax in general, mostly because they've been overwhelmed in recent years by software patents. For example a few years ago, Smuckers received a patent for a crustless PB & J sandwich, and a few weeks ago, Amazon.com received a patent for being able to remember purchasers' histories.)
Yes, every industry has its loopholes that it exploits. These financial officers really do earn their salaries. The man I was talking about earlier as my contact actually created a new tax loophole by directly petitioning the IRS (successfully) on behalf of a deaf client to deduct the cost of his pet. As Oscar Schindler's father told him, there are three things every man needs: a good doctor, a good priest, and a good accountant.
Also, I think that if our tax dollars are going to subsidize these companies, then at the very least, importation needs to be allowed.
I may yet come to agree with you, but as of now, the statement "importation needs to be allowed" is vacuous without qualification. It all depends on what exactly is being imported and what rules this importation follows. Has there been any specific legislation proposed to break the import embargo that I could analyze that has a more detailed plan?
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