- #1
Denver Dang
- 148
- 1
Hi.
I was just curious to how I make these spectras ?
In some of my assignments I have to give a sketch of how a COSY and TOCSY spectra would look like from a given molecule structuere I have and their NMR spectras.
So if I'm not mistaken, in a COSY spectra, I draw the H NMR spectrum on each eaxis, and then draw a dot at the places where there is a direct coupling between hydrogen atoms, right ?
Like if I have:
CH3 - CH2 - CH3,
then CH2 would couple with both CH3, but the CH3's will not couple with each other ? And therefor there is no point/dot for the coordinates where CH3 and CH3 meet ?
Or am I missing something for COSY at least ?
Now, for TOCSY, the CH3's do connect in some way, but my question here is, how far along does hydrogens connect in this type of spectra ?
Again, if I have:
CH3 - CH2 - CH2 - CH2 - CH2 - CH2 - CH3
Does all the H's connect in the TOCSY spectra, or is it just the first 3 or 4 (or something else) within reach ?
So basically, my question is, if I have understood how to do the COSY at least ? And how much coupling there is in TOCSY, and of course, have I totally misunderstood any of it ? :)
Thanks in advance...
I was just curious to how I make these spectras ?
In some of my assignments I have to give a sketch of how a COSY and TOCSY spectra would look like from a given molecule structuere I have and their NMR spectras.
So if I'm not mistaken, in a COSY spectra, I draw the H NMR spectrum on each eaxis, and then draw a dot at the places where there is a direct coupling between hydrogen atoms, right ?
Like if I have:
CH3 - CH2 - CH3,
then CH2 would couple with both CH3, but the CH3's will not couple with each other ? And therefor there is no point/dot for the coordinates where CH3 and CH3 meet ?
Or am I missing something for COSY at least ?
Now, for TOCSY, the CH3's do connect in some way, but my question here is, how far along does hydrogens connect in this type of spectra ?
Again, if I have:
CH3 - CH2 - CH2 - CH2 - CH2 - CH2 - CH3
Does all the H's connect in the TOCSY spectra, or is it just the first 3 or 4 (or something else) within reach ?
So basically, my question is, if I have understood how to do the COSY at least ? And how much coupling there is in TOCSY, and of course, have I totally misunderstood any of it ? :)
Thanks in advance...