Mammalian Enteral Ventilation - a new way to breathe

In summary, a new approach using enteral ventilation has been shown to effectively deliver oxygen to the body through the lower intestinal tract in both mice and pigs. This method, inspired by loaches, utilizes a liquid form of oxygen called conjugated perfluorocarbon and has been found to be highly tolerable and effective for treating severe respiratory failure. This promising development has potential for temporary respiratory assistance in humans as well.
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From: https://www.cell.com/med/fulltext/S2666-6340(21)00153-7?utm_source=EA

Blood oxygenation through the lower intestinal tract is demonstrated in both mice and pigs. It is hoped this wiil work for those Humans that need temporary assistance with respiratory function.

Inspired by organisms such as loaches that use intestinal air breathing, we show the effectiveness of an enteral ventilation approach in attaining systemic oxygenation in both rodent and porcine models. Intra-rectal delivery of a liquid form of O2 known as conjugated perfluorocarbon, a compound historically used in clinics for liquid ventilation through airway administration, is highly tolerable and efficacious in ameliorating severe respiratory failure.
 
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FAQ: Mammalian Enteral Ventilation - a new way to breathe

What is Mammalian Enteral Ventilation?

Mammalian Enteral Ventilation is a new method of breathing that involves delivering oxygen directly to the lungs through a tube inserted into the esophagus. This allows for more efficient and controlled delivery of oxygen to the body.

How does Mammalian Enteral Ventilation work?

In Mammalian Enteral Ventilation, a tube is inserted through the mouth or nose and into the esophagus. Oxygen is then delivered through the tube and into the lungs, bypassing the traditional route of the nose and mouth. This allows for a more direct and efficient delivery of oxygen to the body.

What are the potential benefits of Mammalian Enteral Ventilation?

Mammalian Enteral Ventilation has the potential to improve oxygenation in patients with respiratory failure, reduce the need for invasive mechanical ventilation, and decrease the risk of lung damage. It may also be useful in patients with difficult airway management or those who are unable to tolerate traditional ventilation methods.

Are there any risks associated with Mammalian Enteral Ventilation?

As with any medical procedure, there are potential risks associated with Mammalian Enteral Ventilation. These may include injury to the esophagus or lungs, infection, and air leakage. However, these risks can be minimized with proper training and monitoring by a trained medical professional.

Is Mammalian Enteral Ventilation currently available for use?

While Mammalian Enteral Ventilation is still a relatively new concept, it has been successfully used in animal studies and is currently being studied in human trials. It is not yet widely available for clinical use, but it shows promising potential as a new method of breathing for patients with respiratory failure.

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