To calculate the mean and standard deviation of the product of two variables, the delta method can be applied, utilizing approximation methods like Taylor series or simulation. A key formula to remember is E[XY] = E[X]E[Y] + Cov[X,Y], which requires knowledge of the covariance between the two variables. The discussion highlights the first-order and second-order approximations for the function Y = g(X), emphasizing the importance of understanding the mean and variance of X. SPSS can assist in these calculations, but users may find the formulas complex. Overall, a solid grasp of covariance and approximation techniques is essential for accurate calculations.