Metastisis happens earlier than previously thought

[Astronuc]

Cancer spread 'happens earlier'
http://news.bbc.co.uk/2/hi/health/7586444.stm

Apparently "normal" cells may carry cancer to new sites long before a tumour develops, lying dormant until key genes are activated, experts say.

US researchers say their findings, published in Science, could explain why some breast cancers lead to new tumours long after the disease is treated.

Secondary, or metastatic, cancers are responsible for the majority of deaths from the disease.

UK experts said it was essential to know more about how the cancer spreads.

Something to keep in mind as one ages, and the risk of cancer increases. Prevention is certainly much better than treatment.

 

[Andy Resnick]

Another interesting point is that the secondary tumors are very specific: for example, prostate cancer cells will preferentially seed bone.

The discussion of this effect (among the MDs) is referred to as "the seed or the soil". As in, is this phenomenon due to the cell or to the environment. Yes, it may be both- but the question in that context revolves around treatment options, as opposed to basic science.

 

[oswaler]

I find these findings to be both fascinating and concerning. The concept that cancer cells may be spreading to new sites in the body long before a tumor is even detected goes against what was previously thought about the progression of cancer. This highlights the complexity and adaptability of cancer cells, and the need for continued research to better understand and treat this disease.

The fact that these dormant cancer cells can be activated by certain genes also emphasizes the importance of early detection and prevention. As the risk of cancer increases with age, it is crucial to take proactive measures to reduce that risk, such as maintaining a healthy lifestyle and getting regular screenings.

This study also underscores the significance of studying metastasis and its mechanisms. By understanding how cancer spreads, we can develop more effective treatments and potentially prevent secondary cancers from developing.

In conclusion, this study sheds light on a previously unknown aspect of cancer progression and highlights the need for ongoing research in this field. It also serves as a reminder of the importance of prevention and early detection in the fight against cancer.