- #1
misskitty
- 737
- 0
How do muscle relaxants work and who discovered how they work? Why are there so many different kinds of muscle relaxants? Are there any that are natural?
alpha-neurotoxins Postsynaptic neurotoxins that block the acetylcholine receptor (neuromuscular) Elapid venoms only in snakes, also found in spiders and cone snails
Tetrodotoxin-like acute respiratory failure through paralysis of the respiratory musculature with death as a result Blue-ringed octopi, poison dart frogs, pufferfish
And the poison from dart frogs and the blue-ring octopi can be absorbed through your skin. I checked on plant neuromuscular inhibitors tooThe poison found in pufferfish, blowfish, balloon fish, toads, sunfish, porcupine fish, toadfish, globefish, and swellfish is a tetrodotoxin. This is one of the most toxic poisons found in nature. Most people who eat pufferfish do so intentionally; pufferfish are considered an Asian delicacy, served in some types of sushi and sashimi. Unless the chef is specially trained to cut the meat in a particular fashion, the dish may contain a large amount of the toxin. Pufferfish poisoning is similar to paralytic shellfish poisoning.
Hope you read this.There are 2 basic types of ACh receptors:
Muscarinic type:
Stimulated by the mushroom poison, muscarine
Found in parasympathetic synapses on organs like the heart and intestines; also found in the central nervous system
Nicotinic type:
Stimulated by the plant toxin, nicotine
Found in neuromuscular junctions and autonomic ganglia
Natural ACh receptor inhibitors include:
Curare: South American arrow poison produced from the vine, Chondodendron tomentosum
Atropine: from several plants, including Jimson weed (Datura stramonium), thornapple and nightshade (Belladonna atropa)
Scopolamine: from the henbane plant (Hyoscyamus niger)
Atropine and scopolamine inhibit muscarinic receptors; the other toxins inhibit nicotinic types
Muscle relaxants work by targeting the central nervous system and blocking the nerve impulses that cause muscle contractions. This results in relaxation of the muscles and relief of pain or stiffness.
There are two main types of muscle relaxants: centrally acting and peripherally acting. Centrally acting muscle relaxants target the brain and spinal cord, while peripherally acting muscle relaxants target the muscles directly.
Muscle relaxants are commonly used to treat conditions such as muscle spasms, pain, and stiffness caused by musculoskeletal disorders, such as back pain, neck pain, and fibromyalgia.
Like any medication, there are potential side effects and risks associated with muscle relaxants. It is important to follow the prescribed dosage and consult with a doctor before starting any new medication.
The time it takes for muscle relaxants to start working can vary depending on the type of medication and the individual's response. Some muscle relaxants may start working within 30 minutes, while others may take several hours.