- #1
lha08
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Homework Statement
I'm confused about the N-linked glycosylation process...i know that the precursor is assembled on dolichol phosphate as 3 glucose, 9 mannose and 2 N-acetylglucosamine on the endoplasmic reticulum. After that, apparently it removes some glucose and after that the protein moves to the Golgi, where it removes some mannose to form a core pentasaccharide. But is it in the Golgi that other monosaccharides are added to this core or was it already added in the ER?
I would think its in the Golgi but then again I'm not sure...and also for O-linked i know that its not a preassembled unit and each sugar is added one by one, but again does this occur in the ER or golgi? (not sure, but my hunch is golgi)...