- #1
Star01111
- 3
- 0
- Homework Statement
- I am working on problem 3.7.6 on Strogatz textbook Nonlinear_Dynamics_and_Chaos. It basically says there is a simple model for the evolution of an epidemic. Suppose that the population can be divided into three classes:
x ( t ) = number of healthy people; y ( t ) = number of sick people; z ( t ) = number of
dead people. Assume that the total population remains constant in size, except
for deaths due to the epidemic.
Then the model is
$$\dot x = -kxy$$
$$\dot y = kxy-ly$$
$$\dot z = -ly$$
where k and l are positive constants.
I am fine with a) to f) but having some troubles with g) to j) or k)
g) Show that the maximum of ##\dot u (t)##occurs at the same time as the maximum of both ##\dot z (t)## and ##\dot y (t)##
This time is called the peak of the epidemic, denoted##t_{peak}## peak . At this time, there are more sick people and a higher daily death rate than at any other time.
h) Show that if ##b<1##, then ##/dot u (t)## is increasing at ## t=0## and reaches its maximum at some time ##t_{peak}>0## Thus things get worse before they get better. Show that ##\dot u(t)## eventually decreases to 0.
i) On the other hand, show that ##t_{peak}=0## if ##b>1##. (Hence no epidemic occurs if ##b>1##.
j) The condition b = 1 is the threshold condition for an epidemic to occur. Can you give a biological interpretation of this condition?
k) Kermack and McKendrick showed that their model gave a good fit to data from the Bombay plague of 1906. How would you improve the model to make it more appropriate for AIDS or COVID-19? Which assumptions need revising?
- Relevant Equations
- Some equations that might be useful
$$z\dot = l[N-z-x_{0} exp(-kz(t)/l)]$$
which can be nondimensionalized to $$\frac {du}{d\tau} = a-bu-e^{-u}$$
where $$\tau = kx_0 t$$, $$u=\frac {kz}{l}$$
(I hope my nondimensionalization is correct)
For g) how should I argue this claim? To me it seems straight forward because u is linearly related to z. Then so do their derivatives. And by the description of the model, ##\dot z## is linear to y. So it's quite obvious but not sure what I should pay more attention to when I write my proof.
My main problem starts at h) My attempt is that I take the derivative of ##\dot u(t)## w.r.t. t after rewriting ##\tau## in terms of t. By plugging in the ##z##value at t=0, I can argue the derivative is positive then increasing at ##t=0##. But how should I show its maximum at some time ##t_{peak}>0## and ##\dot u (t)## eventually decreases to 0? I don't have an explicit equation for ##\dot u (t) ## which depends on t. I am getting lost on how to tackle this analytically. Maybe I should solve this completely by drawing the graph and then argue from there?
k) I think the key factor that is missing to implement the model for AIDS and COVID is medical intervention and physically isolation. Both can be represented by a correction term at the end of the model that is first introduced. Am I in the right direction?
Comments: I would say problem a) to f) in 3.7.6 are pretty standard (if someone interested can look it ), but the rest of problem are a bit vague and not described that clearly on how to start. So I would like some help from you guys on this. Thank you so much!
My main problem starts at h) My attempt is that I take the derivative of ##\dot u(t)## w.r.t. t after rewriting ##\tau## in terms of t. By plugging in the ##z##value at t=0, I can argue the derivative is positive then increasing at ##t=0##. But how should I show its maximum at some time ##t_{peak}>0## and ##\dot u (t)## eventually decreases to 0? I don't have an explicit equation for ##\dot u (t) ## which depends on t. I am getting lost on how to tackle this analytically. Maybe I should solve this completely by drawing the graph and then argue from there?
k) I think the key factor that is missing to implement the model for AIDS and COVID is medical intervention and physically isolation. Both can be represented by a correction term at the end of the model that is first introduced. Am I in the right direction?
Comments: I would say problem a) to f) in 3.7.6 are pretty standard (if someone interested can look it ), but the rest of problem are a bit vague and not described that clearly on how to start. So I would like some help from you guys on this. Thank you so much!
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