[Organic Chemistry 1:College] Predict Major Product

In summary, Organic Chemistry 1: College is a course that covers the fundamental principles of organic chemistry and is typically taken by students in their first or second year of college. Predicting major products in organic chemistry allows us to understand the outcome of chemical reactions and design new molecules, and the key concepts to consider include the nature of reactants, type of reaction, stability of intermediates, and regiochemistry and stereoselectivity. Common strategies include identifying the most reactive functional group, considering intermediate stability, and using reaction maps and mechanisms. However, there are limitations such as multiple possible products, side reactions, and the complexity of certain reactions.
  • #1
NY152
25
0

Homework Statement


Predict the major product and type of reaction mechanism (E1/E2/SN1/SN2)

Homework Equations

The Attempt at a Solution


Could someone just double check my work for this? From top to bottom I got: E2, E1, SN1, E1
 

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  • #2
Looks good, but you permuted the last two solutions in the graph.
 
  • #3
NY152 said:

Homework Statement


Predict the major product and type of reaction mechanism (E1/E2/SN1/SN2)

Homework Equations

The Attempt at a Solution


Could someone just double check my work for this? From top to bottom I got: E2, E1, SN1, E1
I think it should be E2(strong base), E2(strong bulky base does E2 hoffman elimination ), E1 and Acid-base reaction followed by Sn1. The bottom two images are shifted tho
 
  • #4
Why do continue to refer to E1/E2 eliminations involving alkyl halides as “Hoffman elimination”?
 
  • #5
chemisttree said:
chemisttree said:
Why do continue to refer to E1/E2 eliminations involving alkyl halides as “Hoffman elimination”?
The second option has tertbutoxide which is a bulky base, it is said to do E2 elimination to form the less stable alkene. Hence Hoffman elimination product is dominant over the zaitsev so it's also called Hoffman Elimination in various chem texts.
 
  • #6
ONLY if the leaving group is a quaternary amine. There are no organic chemistry books that label alkyl halide reactions with strong bases as “Hoffman”.
 
  • #7
chemisttree said:
ONLY if the leaving group is a quaternary amine. There are no organic chemistry books that label alkyl halide reactions with strong bases as “Hoffman”.
By hoffman elimination, I simply mean that the product is a Hoffman product.
 
  • #8
That's not a standard nomenclature and can be misleading and confusing.
 

FAQ: [Organic Chemistry 1:College] Predict Major Product

What is Organic Chemistry 1: College?

Organic Chemistry 1: College is a course that covers the fundamental principles of organic chemistry, including the structure, properties, and reactions of organic compounds. It is typically taken by students in their first or second year of college as part of a chemistry or pre-medical curriculum.

What is the purpose of predicting major products in organic chemistry?

Predicting major products in organic chemistry allows us to understand the outcome of chemical reactions and helps us to design and synthesize new molecules with specific properties. It also helps us to understand the mechanism of a reaction and the factors that influence the product formation.

What are the key concepts to consider when predicting major products in organic chemistry?

The key concepts to consider when predicting major products in organic chemistry include the nature of the reactants, the type of reaction, the stability of intermediates, and the regiochemistry and stereoselectivity of the reaction. Additionally, knowledge of functional groups and their reactivity is crucial in predicting major products.

What are some common strategies for predicting major products in organic chemistry?

Some common strategies for predicting major products in organic chemistry include identifying the most reactive functional group, considering the stability of intermediates, applying the principle of least substituent, and using reaction maps and mechanisms to understand the outcome of a reaction.

Are there any limitations to predicting major products in organic chemistry?

Yes, there are limitations to predicting major products in organic chemistry. These include the presence of multiple possible products, side reactions, and the influence of reaction conditions. Additionally, predicting products in complex reactions can be challenging and may require advanced knowledge of organic chemistry.

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