Quantifying Microtubules in Myelinated Axons

  • Thread starter granpa
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In summary, there are approximately 200-500 microtubules per mylenated axon, based on available research and resources. The exact number may vary, but this is a general estimate.
  • #1
granpa
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how many microtubules are in a cross section of a typical mylenated axon? google brings up lots of hits but most are nonfree and those that arent give no number.
 
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  • #2
I don't have access to the article but from what I can tell I guess a ballpark figure might be around 1000.

http://www3.interscience.wiley.com/journal/109688334/abstract
 
  • #3
granpa said:
I don't have access to the article but from what I can tell I guess a ballpark figure might be around 1000.

http://www3.interscience.wiley.com/journal/109688334/abstract

Normally I may have it in the afternoon.
 
  • #4
I have the paper. Give me an email address (Private Message)
 
  • #5
somasimple said:
I have the paper. Give me an email address (Private Message)

thank you. but I already got it from the library and emailed it to my self. from what I can tell there should be about 200-500 microtubules per axon. I was really expecting more than that.
 

FAQ: Quantifying Microtubules in Myelinated Axons

What are microtubules?

Microtubules are tube-like structures found in cells that are responsible for maintaining the cell's shape, structure, and movement. They are made up of protein subunits called tubulin and are essential for many cellular processes, including cell division and intracellular transport.

How do microtubules function?

Microtubules function by providing structural support to cells and facilitating the transport of materials within the cell. They also play a crucial role in cell division by forming the spindle apparatus that helps separate chromosomes during mitosis and meiosis.

What are myelinated axons?

Myelinated axons are nerve cell fibers surrounded by a fatty substance called myelin. Myelin acts as an insulating layer that helps speed up the transmission of electrical signals along the axon, allowing for more efficient communication between nerve cells.

How are microtubules and myelinated axons related?

Microtubules are essential for the formation and maintenance of myelinated axons. They provide structural support for the axon and help guide the growth of the myelin sheath. Additionally, microtubules are involved in the transport of proteins and lipids necessary for myelin production.

What happens if microtubule function is disrupted?

If microtubule function is disrupted, it can lead to various cellular and neurological disorders. For example, mutations in genes that code for microtubule proteins have been linked to neurodegenerative diseases such as Alzheimer's and Parkinson's. Disruption of microtubule function can also affect the proper functioning of myelinated axons and contribute to conditions such as multiple sclerosis.

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