Response of erythrocytes using 2 way FSI?

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In summary, the conversation revolved around a 2-way Fluid structure interaction project related to RBC in capillaries. The speaker discussed designing a micro-scale shell RBC and a fluid medium with specific parameters. They also mentioned defining fluid surface interfaces and assumptions made in the analysis. The speaker then shared their difficulties in running the analysis and asked for explanations on the results. The other person responded by explaining the potential issues with small clearances and high speeds in simulation systems.
  • #1
Mitra Lanka
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Hi,
I am working on a 2-way Fluid structure interaction project related to RBC in capillaries.

I have designed a micro-scale shell RBC and a fluid medium which has diameter just above the dia of RBC. In the transient structural analysis I have defined two fluid surface interfaces: 1. Exterior portion of RBC 2. Interior portion of RBC.

In the Fluent medium I have defined the walls, boundaries of capillary tube and cytoplasm (hollow portion of RBC) which are supposed to interact with with the solid RBC in Transient. I have assumed that blood runs at x velocity and cytoplasm relatively at 0.97x velocity.

Similarly, in transient I have 0.97x velocity, 9.7x displacement to Solid RBC When I run the analysis by coupling both systems I receive error by doing so. But if I reduce the time step (0.0004) sec for 10 sub-steps ,velocity to 0.0000097x and displacement by 0.000097x solution runs smoothly.

Irrespective of correctness of result, Could anyone tell me why is that if i decrease the velocity, displacement and time steps there is result and why if i consider real time scenario this does not work?

Thanks
 
  • #3
Most simulation systems will have problems with small clearances with high speeds because the discrete time steps needed become very short and it takes too much time to solve the matrices.

Is this a question about ANSYS Fluent simulation software ?
 

FAQ: Response of erythrocytes using 2 way FSI?

What is the purpose of studying the response of erythrocytes using 2 way FSI?

The purpose of studying the response of erythrocytes using 2 way FSI is to understand how these cells behave under different fluid flow conditions. This can help in designing more effective drug delivery systems and improving our understanding of diseases that affect erythrocytes.

What is 2 way FSI and how is it used in this study?

2 way FSI stands for two-way fluid structure interaction and it is a computational method used to simulate the interaction between fluids and structures. In this study, it is used to simulate the flow of fluid around erythrocytes and how the cells respond to this fluid flow.

What are the main findings of this study?

The main findings of this study include the identification of different deformation patterns of erythrocytes under varying fluid flow conditions, the impact of cell shape on its response to fluid flow, and the development of a mathematical model to predict the behavior of erythrocytes in different flow conditions.

How can this research benefit the medical field?

This research can benefit the medical field by providing a better understanding of how erythrocytes behave in different flow conditions. This can help in the development of more efficient drug delivery systems for diseases that affect erythrocytes, such as sickle cell anemia. It can also aid in the diagnosis and treatment of various blood disorders.

What are the potential future applications of this research?

The potential future applications of this research include the development of more accurate models for simulating blood flow in the body, which can aid in the diagnosis and treatment of cardiovascular diseases. It can also be used to improve the design of medical devices, such as artificial organs and blood pumps, by considering the behavior of erythrocytes in fluid flow.

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