Sirtuins genes used to increase lifespan

In summary, the book Lifespan by David Sinclair discusses the potential for increasing lifespan through the use of Sirtuin genes (SIRT1 to SIRT7). These genes have been shown to repair epi-genetic damage and extend mice lifespans by 20%. Human trials are expected to begin in the next few years. There is interest in this research and a desire for a forum to discuss and share information about it.
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brajesh
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TL;DR Summary
Increasing lifespan - Sirtuins and genes
I read this book called Lifespan by a Harvard researcher called David Sinclair.
They have found that Sirtuin genes (SIRT1 to SIRT7) help in repairing epi-genetic damage and have been able to extend mice lifespans by 20%.
They are going to move to human trials within the next few years.

Is anyone following this research? Is there a forum where we could share/discuss this information?
 
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brajesh said:
Summary:: Increasing lifespan - Sirtuins and genes

I read this book called Lifespan by a Harvard researcher called David Sinclair.
They have found that Sirtuin genes (SIRT1 to SIRT7) help in repairing epi-genetic damage and have been able to extend mice lifespans by 20%.
They are going to move to human trials within the next few years.

Is anyone following this research? Is there a forum where we could share/discuss this information?
Most of us could extend our expected lifespan 20% if we just followed our doctor's advice but we don't.
 
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FAQ: Sirtuins genes used to increase lifespan

What are sirtuin genes?

Sirtuin genes are a group of genes that are involved in regulating various cellular processes, including aging and longevity. They are found in all living organisms, from bacteria to humans.

How do sirtuin genes affect lifespan?

Sirtuin genes are known to play a role in extending lifespan by promoting cellular repair and maintenance. They also regulate the expression of other genes involved in metabolism and stress response, which can impact overall health and longevity.

Can sirtuin genes be manipulated to increase lifespan?

Research has shown that sirtuin genes can be activated or inhibited through various interventions, such as caloric restriction and exercise. However, the exact mechanisms and potential risks of manipulating these genes for lifespan extension are still being studied.

Are there any known benefits of sirtuin gene activation?

Aside from potentially increasing lifespan, sirtuin gene activation has been linked to improved metabolic health, reduced inflammation, and increased stress resistance. However, more research is needed to fully understand the effects and potential benefits of sirtuin gene activation.

Are there any potential risks of sirtuin gene manipulation?

While sirtuin gene activation has shown potential benefits, there are also concerns about potential risks, such as disrupting normal cellular processes and promoting tumor growth. More research is needed to fully understand the safety and efficacy of manipulating sirtuin genes.

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