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mktsgm
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- Is there a structural difference between mature B cells and memory B cells?
I have the following doubts regarding B cells.
Normally upon the stimulation by a T-cell, the activated B-cell differentiates into plasma and memory cells.
1) What are the structural differences among the naive B-cells, activated B-cells, Plasma B-cells, and memory B-cells? I am interested in the comparison of structures of Plasma B-cells and memory B-cells.
2) Is it possible to detect and measure all four?
a) Again I am particularly interested in the Plasma B-cells and memory B-cells for a particular antigen. How do we differentiate between them and can we detect and measure them?
Thanks in advance,
Normally upon the stimulation by a T-cell, the activated B-cell differentiates into plasma and memory cells.
1) What are the structural differences among the naive B-cells, activated B-cells, Plasma B-cells, and memory B-cells? I am interested in the comparison of structures of Plasma B-cells and memory B-cells.
2) Is it possible to detect and measure all four?
a) Again I am particularly interested in the Plasma B-cells and memory B-cells for a particular antigen. How do we differentiate between them and can we detect and measure them?
Thanks in advance,