Disease Definition and 135 Threads

I've never heard of this rare disease/illness. I just learned about it from a news feed from a case in Yorkshire, England. https://www.manchestereveningnews.co.uk/news/uk-news/man-30-died-suddenly-after-25915295 https://www.frontiersin.org/articles/10.3389/fimmu.2021.773352/full It's...

The first picture is the image given in the question, and the second picture is the possible genotypes given in the solution manual. How is it possible that person II.1 (first male in the second generation) has the genotype A/- when he is unaffected? I thought that because person II.1 and...

https://abcnews.go.com/International/tanzania-investigates-deadly-outbreak-mystery-disease/story?id=86870310 https://www.ndtv.com/world-news/mysterious-ebola-like-disease-kills-3-in-tanzania-probe-launched-3158007 The outbreak in Tanzania comes days after Ghana reported two suspected cases of...

I saw this on the local TV news tonight (I live in Silicon Valley not far from Stanford). It looks to be a very promising and innovative treatment for Parkinson's Disease that is showing some amazing early results (led by Stanford Medicine researcher Peter Tass, MD, PhD). They are calling for...

In the "Results" section of the Abstract of https://pubmed.ncbi.nlm.nih.gov/23708150/, (due to a paywall, I get no further) there is the following "The dose-response RR of CHD for an increase in heme iron intake of 1 mg/day was 1.27" (CHD being coronary heart disease). Is the paraphrasing in...

A teen ate leftover rice and noodles. Hours later, doctors amputated his legs and fingers https://www.usatoday.com/story/news/health/2022/02/22/leftover-food-disease-amputated-legs-fingers/6890754001/ The article later mentions bacterium . . ...

[url="https://www.physicsforums.com/insights/probabilistic-factors-involved-in-disease-and-virus-testing/"]Continue reading...

My wife read an article last night about an outbreak of hemorrhagic fever in rabbits, and it has been passing through populations throughout the US. So, I decided to look into it and came across a wildlifehealth.org. There is a lot of nasty stuff out there. Detection of High Pathogenic Avian...

From the Oligonucleotide Therapeutics Society: "Can Oligonucleotides Target RNA Splicing to Treat Disease?" https://www.oligotherapeutics.org/can-oligonucleotides-target-rna-splicing-to-treat-disease/

Could someone age and get old without any chronic disease, even the most common diseases like diabetes, heart attack, high blood pressure, etc... not including hair loss, presbyopia, or any disease that is temporary and can heal completely Is it possible to achieve this by change in lifestyle...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608552/ Do you think this is already 100% accepted by the medical and scientific world? It says that if you are born Small for Gestational Age. You would get all kinds of diseases like diabetes, hypertension, coronary diseases, mental diseases etc...

NY Times - A Terrifying Disease Stalks Seaside Australia: Flesh-Eating Ulcers https://news.yahoo.com/terrifying-disease-stalks-seaside-australia-120741684.html What looked like a sunburn on the top of a man's foot turned out to be an infection of a species of flesh-eating bacteria! The species...

Hello at all! I have to solve this exercise: A tampon diagnostic test provides 1% positive results. The positive predictive values (probabilities of positive test disease) and negative (absence disease given negative test) are respectively 0.95 and 0.98. What is the prevalence of the disease...

I came across one article, and I've been looking for similar articles for other nations or groups, e.g., EU. Mortality from heart disease apparently spikes around Winter Solstice and Christmas (end of the calendar year), as well as other causes, which may be related, e.g., obesity and diabetes...

What is the rate of Covid-19 infection compared to the rate of immune response? Faster, slower? Consider two scenarios: Scenario 1: Small initial exposure to Covid-19. Person is briefly exposed to Covid. They perhaps touch infected surface and touch inside of their nose. Scenario 2...

“Effect of Omega-3 Dosage on Cardiovascular Outcomes: An Updated Meta-Analysis and Meta-Regression of Interventional Trials” by Aldo A. Bernasconi, PhD; Michelle M. Wiest, PhD; Carl J. Lavie, MD; Richard V. Milani, MD; and Jari A. Laukkanen, MD, PhD, 17 September 2020, Mayo Clinic Proceedings...

This has come up in the press the last few days that they now believe Covid-19 is not just a respiratory disease. This is a very interesting article on it. It explains the virus and how it works. https://www.ucsf.edu/magazine/covid-body

The Journal of the American Medical Association (JAMA) today (7/28/2020) published an article on using presence of phospho-tau217 (p-tau217) in blood plasma to detect Alzheimers Disease. Over 80% specificity, and early results look like it could be predictive up to 20 years...

It is said that necrosis precipitates inflammation. It is also considered that inflammation causes most of the damage in any diseased condition. Comparatively, apoptosis doesn't trigger inflammation. I have the following doubts in this context. 1) Is necrotic (and/or apoptotic) cell death...

This DE is related to a mathematical model of the spread of an infectious disease: $$f'\left(x\right)=a\cdot\left[f\left(x\right)-f\left(x-b\right)\right]$$ where a and b are positive constants. I would like some pointers as to how I should begin attempting to solve it.

I'm considering a dynamical model of the scenario of a disease spreading across the population, modelling the number of cases, and there's a mathematical puzzle which I'd like to solve. It's kinda different from the S-I-R model, and its also a crude model. First, we consider two numbers, NT...

I'm trying to dynamically model the scenario of a disease spreading across the population, modelling the number of cases, and I would love to hear your feedback. It's kinda different from the S-I-R model, and its also a crude model. First, we consider two numbers, NT and NA. NT is the total...

According to the CDC 1 out of 102 persons who are males of a particular demographic have HIV. That mean's there is 1/102 = .98 * 100 = 1% chance of having HIV. There is a swab HIV test available that is 91.7% accurate at being able to identify HIV positive people. This means that 12 out of 13...

Hey, I'm writing a science-fiction novel, and trying to keep as much "sci" in there as I can! Scenario: A character has been successfully cured of a deadly disease, using cool (insert hand wave) stuff. But all records of the cure have been destroyed (files of info, samples, etc). Now the...

I'm hoping a mod can move this to the biology forum section, I keep trying to post in it, but every time I click on the biology forums I'm automatically logged out. I've read about how sometimes the DNA polymerase inserts a wrong amino acid and ends up modifying the DNA rather than the RNA...

Hello people, For a project I am working on I am looking for more detailed information on clinical issues that may arise in vWD in dogs. The focus for us is on a specific breed of dogs, but first we need some data from different breeds to have a benchmark. Does anyone here happen to know...

Is there any research or study which is to estimate the weight of genetics in preventing one or more diseases compared to other factors? A lot of time, for example, explaining how a particular kind of cancer occurs in someone, genetics is often mentioned, in addition to other factors, but how...

A Science mag news article describes a rare disease (acute flaccid myelitis) that can cause Polio-like symptoms has been found in 22 of the US states. It may (or may not) be due to the enterovirus D68 (EV-D68), a polio relative. The virus is thought to normally cause mild flu symptoms, but its...

I have been looking for biomarkers for Alzheimer's disease which can be detected in structural MRI. I have gone through some papers and found that Gray matter, white matter and CSF are good biomarkers. But is there any other except?

Recently, John McCain died of glioblastoma (brain cancer.) The odds of dying on particular date is 1 in 365. He died of the same disease as did Ted Kennedy, on the very same date that Kennedy did. Glioblastoma affects 3.1 in 100,000 population. The mean average life span living with the...

What muscle or tendon is involved when you tried to touch the armpit of the other side of the body and there is slight muscle or tendon pain for the arms that reached out to the other armpit ? I feel some mild muscle pain last night after gym and just want to see the anatomy involved. I'm not...

Homework Statement Produce an detailed understandsing of the anatomy and function of the lymphatic system, using correct scientific terminology to explain the rationale for use of corrective treatment for lymphedema. Homework Equations N/A The Attempt at a Solution Lymphatic edema is the...

Homework Statement How does Hodgkin's lymphoma effect the "normal" function of the lymphatic system? Homework Equations N/A The Attempt at a Solution After research I have found out that HL casues lymph nodes to become inflames. I have concluded HL causes lymph fluid to get blocked at lymph...

How do you think Stephen Hawking would have been if he didn't have the disease that he had and wasn't physically handicapped?

Hey! :o The percentage of people that have a disease A is $0,01$. We apply twice a test for that disease, each of which give the correct answer with probability $0,95$. What is the probability that someone has that disease if at least one test is positive and what is the probability if both...

I have been sitting in front of a computer for more than 10 hours/day for about three years. I feel considerable pain in my arms and legs all the time, although they appear more serious during the night. The medical recommendation is to do exercises. My question is, if I exercise myself from now...

NIH news release: https://www.nih.gov/news-events/news-releases/higher-brain-glucose-levels-may-mean-more-severe-alzheimers To start with, this does NOT prove a link between glucose blood levels and Alzheimers onset. Or more simply put, this paper does not say: sugar causes Alzheimers. Why...

Sorry for being annoying, but I am a student of physics for a month now. I started really well by setting up super good work habbits but all was ruined in a day when I was arguing with my parents about my treatment for my desiese. Since then everything has been hell, I fell behind bad, I am...

From meeting of cardiologists in Spain: Study on +135000 people worldwide, researchers interpretation: Note that the study included many residents of third world countries where macronutrient (fats and carbohydrates) over consumption is not common. For biology types...

I started having appendicitis 3 nights ago. It woke me up from sleep with lots of pain and nausea. I took pepto-bismol for the nausea but despite the fact that it had salicylic acid which is the prodrug of aspirin and releives pain by affecting genetic expression of the COX enzyme that forms...

https://link.springer.com/article/10.1007/s10654-017-0243-1 Jung Huo et al, 2017 European Journal of Epidemiology, 'Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose–response meta-analysis of prospective cohort studies' The takeaway is that saturated...

The links to the studies are in the article. Those with celiac disease often follow strict gluten-free diets, because consuming the protein found in wheat, rye, and barley can cause them to develop health problems and gastrointestinal issues. And yet, certain people seeking to lose weight have...

This is a disease I have not heard of, and it seems not many Americans are aware of it, It seems it causes heart failure in many Latin Americans. https://www.sciencedaily.com/releases/2015/09/150909132742.htm As it may not be detected by medical staff and it seems not many are aware of it...

present time we just knew that US Government legalized the use of marijuana cigarettes. Is there any proven that marijuana can heal parkinson disease and also can heal cancer.

People generally associate Gastroesophageal reflux disease (GERD) with excessive production of hydrochloric acid in the stomach. We know that HCL is essential for proper digestion. In acid reflux the acid comes up the esophagus from the stomach due to the insufficiency of esophageal sphincter...

this is something I was born with or at least it was affecting me by the time i was 3-6 years of age. I am almost 40 now and I still have no idea what causes crohn's. I know it an autoimmune thing (and yes I know what that means) but what cause it to happen? why does my body hate it self so...

I just finishedOn the Origin of Species. It seems Darwin is saying that characteristics that make it less likely for an organism to survive will drop out over time. But other scientists tell me that cancer has a genetic link, that suicide has a genetic predisposition, etc. Many diseases have...

Hello everyone, Let's take a woman with a breast lump for example and it is malignant. I know that stage 3 and 4 disease, eg advanced/metastatic disease treatment is chemotherapy/radiotherapy. Then after it is downgraded they surgically resect the lump (stage 1 and 2). While this makes sense my...

After watching "Still Alice"(starring Juliane Moore) which is about an Alzheimer's patient, I started thinking about this disease a little bit and suddenly it occurred to me that its plausible to expect seeing such an effect in neural networks too. I mean, imagine you have a neural network that...

I have looked in a lot of different websites for a explanation of the mechanism of the ebolavirus to infect our body: how it avoid our immunology system, what it exactly change from our DNA and the consequences in the body. I didn't found a clear information, can someone help me to understand ebola?