Does NH[SUB]3[/SUB] react with aldehyde ?

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In summary, the reaction between NH<sub>3</sub> and aldehyde is a reversible condensation reaction that forms an imine compound and water. The rate of this reaction can be affected by factors such as reactant concentrations, temperature, and the presence of catalysts and functional groups. This reaction has various applications in organic synthesis, including the production of pharmaceuticals and industrial chemicals.
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leojun
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does NH3 react with compounds having aldehydic group?(if,yes.why doesn't glucose react with NH3. 0.02% of glucose has open chain structure that has free aldehydic group) In my textbook its given that NH3 doesn't react with glucose and this led to the conclusion that glucose had ring structure with no free aldehydic group.
 
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  • #2
Ammonia (or amines) plus aldehydes do react to form imines; the reaction is acid catalyzed (pH dependent), and pH of the "0.02% open chain glucose" might interfere.
 

FAQ: Does NH[SUB]3[/SUB] react with aldehyde ?

What is the reaction between NH3 and aldehyde?

The reaction between NH3 (ammonia) and aldehyde is a condensation reaction, forming an imine compound. This reaction involves the substitution of the carbonyl group in the aldehyde with an NH2 group from ammonia.

What are the products of the reaction between NH3 and aldehyde?

The products of this reaction are an imine compound (formed by the substitution of the carbonyl group in the aldehyde with an NH2 group from ammonia) and water. In some cases, a secondary amine may also be formed as a byproduct.

Is the reaction between NH3 and aldehyde reversible?

Yes, the reaction between NH3 and aldehyde is reversible. Under certain conditions, the imine compound formed can react with water to regenerate the original aldehyde and ammonia. This equilibrium can be shifted towards the products by using excess ammonia or by removing water from the reaction mixture.

What factors can affect the reaction between NH3 and aldehyde?

The rate of the reaction between NH3 and aldehyde can be affected by several factors such as the concentration and reactivity of the aldehyde, the concentration of ammonia, the temperature, and the presence of catalysts. Additionally, the presence of other functional groups on the aldehyde can also influence the reaction.

What are some applications of the reaction between NH3 and aldehyde?

The reaction between NH3 and aldehyde has various applications in organic synthesis. It is commonly used to synthesize imine compounds, which can then be further reacted to produce a variety of other compounds such as amines, amides, and nitriles. This reaction is also used in the production of pharmaceuticals, dyes, and other industrial chemicals.

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