Fetal Lamb in a Bag: Scientists Hope to Replicate for Humans

  • Thread starter Thread starter BillTre
  • Start date Start date
AI Thread Summary
Scientists have successfully used plastic bags to replicate amniotic sacs and plumbing to replace placentas in fetal lambs, with aspirations to apply this technology to premature human infants. There is uncertainty regarding the role of the placenta, particularly its hormonal effects, and how these might be replicated in a synthetic environment. The discussion highlights that while neonatal intensive care currently relies on incubators, a synthetic placenta could represent a significant advancement in care for premature infants. The technology remains experimental, and future iterations are expected to incorporate more features of natural placental function.
BillTre
Science Advisor
Gold Member
2024 Award
Messages
2,686
Reaction score
11,719
Scientists have been able to bring fetal lambs to term using plastic bags to replace their normal amniotic sacks and a bit of plumbing to replace the placenta. They hope to do this with premature humans eventually.

Not sure about the placental replacement part since I thought the placenta had some hormonal effects on the fetus, but maybe that's only at earlier stages or for the mother.
 
Biology news on Phys.org
For premies, maturing within the sack or outside, the placenta isn't available in either case.
This is not for embryonic development to maturity, as that I would think would be years away.
Even the "placental fluid" is not much more than a saline solution for the sack.
 
@256bits -
maturing within the sack or outside, the placenta isn't available in either case.
This does not make sense to me, can you please explain? They are going to supplant/replace the placenta. My take on it, anyway.
 
jim mcnamara said:
@256bits -

This does not make sense to me, can you please explain? They are going to supplant/replace the placenta. My take on it, anyway.
Presently neonatal intensive care for premature is through an incubation unit.
https://en.wikipedia.org/wiki/Neonatal_intensive_care_unit
So it would be a step forward I believe, to have a placenta type care unit.
As this is a prototype and experimental, it's features would change in future use for humans, with more placental features.
 
Haha haha yes one step closer to:woot: !... Um oh I er yes that is very interesting:wink:
 
I've been reading a bunch of articles in this month's Scientific American on Alzheimer's and ran across this article in a web feed that I subscribe to. The SA articles that I've read so far have touched on issues with the blood-brain barrier but this appears to be a novel approach to the problem - fix the exit ramp and the brain clears out the plaques. https://www.sciencealert.com/new-alzheimers-treatment-clears-plaques-from-brains-of-mice-within-hours The original paper: Rapid amyloid-β...
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) The structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Back
Top