How do I synthesize Cedryl Acetate for perfumery?

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In summary, synthesizing Cedryl Acetate for perfumery typically involves the acylation of cedrol with acetic anhydride or acetyl chloride in the presence of a catalyst, such as pyridine. The reaction produces Cedryl Acetate, which is then purified through distillation or chromatography. This compound is valued in perfumery for its woody and floral notes, contributing to various fragrance formulations. Proper handling and safety measures are essential during the synthesis process.
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krasss
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I wanna synthesize 10 ml of Cedryl Acetate for my perfume. How can i do it?
 
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  • #2
Why? Isn't that like $1 worth?
 
  • #3
Vanadium 50 said:
Why? Isn't that like $1 worth?
Not in here...
 
  • #5
This is simple ester so synthesis is probably rather trivial if you have access to lab glass, but you will still need to buy cedrol - so why not save yourself unnecessary work and buy cedryl acetate instead?
 
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Do you have access to pure cedrol? If not, you will need to obtain cedar oil and perform a fractional vacuum distillation.
There are multiple ways to make acetate esters but since those methods are used to make heroin as well…. you could be scrutinized by who knows? Most of the reagents that are easily obtained are on “diversion” lists and purchases are watched.

Best to just buy some?
 
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  • #7
chemisttree said:
since those methods are used to make heroin as wel
Oh my.
 
  • #8
:eek:... Entertaining the gentlemen wearing sport jackets and shoulder holsters is NOT conducive to 'Live Long and Prosper'; regardless of which side they are on!
 
  • #9
Vanadium 50 said:
Oh my.

While it is definitely true that acylation is used in some drug synthesis procedures, it is a bit like claiming screwdrivers are for repairing guns.

Esterification with acetic acid (and the reverse process, hydrolysis of esters) are between those basic things commonly used in ChemOrg101 labs. Trivial to understand, in many basic cases simple to set up.
 
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  • #10
Whew!

Still, it seems very odd to want to synthesize something that costs a few dollars at most. Heck, the glassware is more expensive!
 
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Glassware is on watchlists as well. After leaving my research job at SwRI, I set up a lab from scratch. I was required to label and inventory almost all of my glassware and report it to the Texas Department of Public Safety. A Trooper came out to inspect my lab and paperwork!

Don’t Mess With Texas!
 
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chemisttree said:
Don’t Mess With Texas!
Or they may Tread On YOU! :wink:
 
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  • #13
Tom.G said:
Or they may Tread On YOU
I think that's South Carolina.
Or Soviet Russia. :smile:
 
  • #14
You are certainly a lot closer than I was!

I remembered it as a Texas flag with a Rattlesnack and saying "Dont Tread On Me".

However Google/Wikipedia state, among other things, that:
In the United States military, the phrase is the motto of the US Army's oldest infantry regiment, the 3rd U.S. Infantry Regiment (The Old Guard), located at Fort Myer, Virginia. "Don't tread on me" is also used in the First Navy Jack of United States Navy.

(from:
https://www.google.com/search?hl=en&source=hp&biw=&bih=&q=don't+tread+on+me+political+meaning)
 

FAQ: How do I synthesize Cedryl Acetate for perfumery?

How do I obtain Cedryl Acetate for perfumery?

To synthesize Cedryl Acetate for perfumery, you will need to react Cedrol with acetic anhydride in the presence of a catalyst such as sulfuric acid. This reaction will yield Cedryl Acetate, which can then be isolated and purified for use in perfumery.

What is the chemical structure of Cedryl Acetate?

Cedryl Acetate has the chemical formula C16H26O2 and is a derivative of Cedrol. It is an ester formed from the reaction between Cedrol and acetic acid, resulting in a sweet, woody scent commonly used in perfumery.

What are the properties of Cedryl Acetate in perfumery?

Cedryl Acetate is known for its warm, woody aroma with hints of cedar and sandalwood. It is often used as a base note in perfumery to add depth and longevity to fragrance compositions. Additionally, Cedryl Acetate is valued for its fixative properties, helping to anchor other volatile fragrance components.

Can I purchase Cedryl Acetate for perfumery purposes?

While Cedryl Acetate can be purchased from various suppliers specializing in fragrance ingredients, some perfumers prefer to synthesize it in-house for greater control over the quality and purity of the compound. If you choose to purchase Cedryl Acetate, be sure to source it from a reputable supplier to ensure its authenticity and quality.

Are there any safety considerations when working with Cedryl Acetate?

As with handling any chemical compound, it is important to take proper safety precautions when working with Cedryl Acetate. This includes wearing appropriate personal protective equipment, such as gloves and goggles, and working in a well-ventilated area to minimize exposure to vapors. Additionally, be sure to follow established protocols for handling and storing chemicals to prevent accidents and ensure your safety.

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