- #1
awkwardsilence
- 1
- 0
Hey you guys! I'm a med student from Sweden in need of some help!
I'm doing a summer course type-a thing in a lab, and I have to present some data from a project I've been doing here. Now, I've tested several genes' expression and I've compared those of an experimental group to a control group. Now that I'm done with the experiments, I've found that some genes show a significant difference in expression between exp. group and ctrl group, and others do not. I think two of the genes are more likely then the others to in reality have equal expression of the gene, in both the groups, but I can't prove a null hypothesis with a t-test...
So, my question now is HOW do I calculate equivalence (and get as close as possible to proving the two samples are equal)?
How do I calculate this in an easy way? (Excel/ online test)
From what I understand, there's one type of test where you calculate two(?) p-values with a regular t-test, then subtract from each other and it should be less p=0.10. I don't really understand it though... Like what two p-values could I get from the same samples? :S
I'd love to get an answer from any of you, if you have an idea about how to solve my problem!
I'm doing a summer course type-a thing in a lab, and I have to present some data from a project I've been doing here. Now, I've tested several genes' expression and I've compared those of an experimental group to a control group. Now that I'm done with the experiments, I've found that some genes show a significant difference in expression between exp. group and ctrl group, and others do not. I think two of the genes are more likely then the others to in reality have equal expression of the gene, in both the groups, but I can't prove a null hypothesis with a t-test...
So, my question now is HOW do I calculate equivalence (and get as close as possible to proving the two samples are equal)?
How do I calculate this in an easy way? (Excel/ online test)
From what I understand, there's one type of test where you calculate two(?) p-values with a regular t-test, then subtract from each other and it should be less p=0.10. I don't really understand it though... Like what two p-values could I get from the same samples? :S
I'd love to get an answer from any of you, if you have an idea about how to solve my problem!