I got my biology degree in 1979 and would like to get current again on DNA. What would you suggest? I'm in Japan so access to English books is quite limited.
Hi,
I have e hypothetical question. (I'm a thriller author and am stuck on my knowlegde on DNA). I've tried to google this for a few days now, but I guess I'm doing it wrong.
So let's say a newborn is found by a couple on their porch. It's not theirs and not their daughter's so they take it to...
I'm asking in order to understand if the only difference between the DNA of all living things is merely the arrangement or sequence of their letters. This is more of a curiosity question, not about sci-fi or current feasibility.
Could the letters of a human DNA be reordered so it's identical to...
Unfortunately, I have problems with the following task
For task 1, I proceeded as follows. Since the four bases have the same probability, this is ##P=\frac{1}{4}## I then simply used this probability in the formula for the Shannon entropy...
Hi
It is about a DNA strand on which there are always two segments, the segment ##A##, which is folded and has the length ##l_A## and the unfolded segment ##B##, which has ##l_B+\lambda##. Here is a section of the DNA
There is now, as shown in the picture, a force ##F## pulling on the...
I'm designing a ... let's call it a sculpture. It represents DNA.
I just realized there are (at least) two ways helices can spiral together:
A has two helices that are concentric but with different radii. They are also "in phase".
B has two identical helices that are "out-of-phase" by 180...
Summary: Curious to find out genetic code other than DNA
<mentor> Moved to Discussion, hypothetical discussion
Dear PF Forum,
It's been a long time since I log into PF. And I hope everybody is in a good health.
Recently I had a discussion debate with my friend about other life in this...
I refer to the tables on https://en.wikipedia.org/wiki/DNA_and_RNA_codon_tables
In both the DNA and the RNA codon tables, ACG codes for threonine. But the transcription of the ACG from the DNA to the mRNA ends up with UGC (which would code for Cysteine). So should I assume that when the DNA...
I recently took a DNA test in parallel with collecting family records, government records, and church records (many of which are used by local/regional governments). I knew about many ancestors, but I've confirmed many more through discovering other family lines through DNA tests. I've...
It is well known that RNA viruses mutate very quickly. Hence, it is said that it is very hard to develop an effective vaccine against it. With HIV and influenza RNA viruses the scientific world is still facing difficulty in developing effective long-term vaccines against them. Most influenza...
The answer is that there would only be a 250 bp fragment, and it would be brighter.
I think that there would just more fragments of all sizes, as more DNA is degraded. I don't understand why there wouldn't be fragments of larger sizes. Thanks!
In my understanding, in the human host, the Oxford–AstraZeneca vaccine delivers the DNA genetic code for the production of spike proteins of the SARS-CoV2 virus, inside a vector virus. DNA vaccines deliver them through plasmids.
Apart from this delivery mode, is there any difference between the...
We know that ##P(A-) = (95\% \cdot 0.5\% + 5\% \cdot 98.5\% )## and ##P(guilty \ and \ A-) = (95\% \cdot 0.5\%)##, so letter a) is just ##P(guilty \ and \ A-)/P(A-)##.
What I tried to do in letter b) was again using the conditional probability theorem. First calculating the probability that...
This is the first time I am working with DNA and I have to dissolve the dried oligos in PBS( 10mM phosphate buffer, 100mM NaCl, ph=7.4) buffer. However I don't understand how to do that. I will really appreciate if somebody can please explain me. Thank you in advance.
Here's the story:
I did the 23&Me and it told me that I was about 90% X but then there was among the smaller %ages a Y = French
Later, about a year later, I checked it again. The French ancestry had disappeared. There was still 90% X, but now I had a Y = Scandinavia.
So, I ran the test again...
I understand that DNA strands have two sides with amino acids, and that the amino acids connect to each other by being the opposite of each other (A-T, C-G). I also understand that the reproductory DNA of the organisms reproducing each consist of one side of each of the DNA strands, that...
I was just reading about DNA sequencing. In my view, DNA can be modeled into an ordered sequence of nucleobases, as if the two strands were joined into a single strand (just like in RNA). The first half of the sequence models the first strand. The four nucleobases are numbered from 0 to 3...
Hi all,
In light of recent findings about Topoisomerase-mediated DNA double strand breaks, I have been looking for a study out there that compares cummulative DNA damage in active neurons vs. less active counterparts. So far I have not been able to find anything - this would hopefully be over a...
This was published in Feb
https://www.pnas.org/content/117/10/5358
The genes relating to mitochondria in this parasite of Salmon are absent which is a first to see in a multi cellular animal.
Is there any DNA, biology, genetics and genealogy tests that i can take to find out what i am supposed to do naturally OR what I am naturally made for? for example, my sexuality or being straight, bisexual, gay. If yes, what do these tests tell me about my DNA, biology and/or genes? Even if its...
I found this article on https://www.researchgate.net/publication/339566392_Evidence_of_proteins_chromosomes_and_chemical_markers_of_DNA_in_exceptionally_preserved_dinosaur_cartilage.
The reference is:
Alida M. Bailleul, Wenxia Zheng, John R. Horner , Brian K. Hall, Casey M. Holliday and Mary H...
I often read that whenever a new fossil is found (like a bone fragment or skull fragment etc) they trace it back to either some animal or human , now mostly (and before DNA testing was possible) this was done I suppose by visual inspection and "radiocarbon" dating to put the fossil in a...
Hello,
I am not sure if this an odd or even an ignorant question or not, but I will give it a try.
I understand that the adaptive immune system "saves viral DNA" as antibodies to potentially "use" it in the future, if the antigens ever "return". I also understand that "antigens" are "virus...
Over the past half decade, researchers have envisioned the https://www.physicsforums.com/insights/dont-fear-https://www.physicsforums.com/insights/dont-fear-crispr-new-gene-editing-technologies-wont-lead-designer-babies/-new-gene-editing-technologies-wont-lead-designer-babies/system as a way to...
Popular precis:
https://www.aging-us.com/dna-methylation-grimage-strongly-predicts-lifespan-and-healthspan Ake Lu, Steve Horvath
David Geffen School of Medicine at UCLA
My take:
While DNA may change anywhere due to methylation, so that cells in a given tissue may have different damage points...
Greetings
Since genome sequencing is apparently having a major impact on medical science, just to name one field, I am interested in hearing/reading more about this recent event regarding autism. It seems to me this could have far-reaching implications and possibly major impact on how we view...
As DNA sequence information from individual patients becomes more available, and the amount of information associated with particular sequence variants increases, this kind of collection and analysis of sequence data will assume great importance to medical practitioners.
With medical importance...
Interesting video on DNA and privacy in today's world:
Specifically folks in some instances can be identified from their relatives DNA.
The worry of course is false positives placing you at a crime scene or of a sketchy insurance company profiling you and refusing coverage based on what...
Published this week in the journal Science, researchers report that they have devised a eight letter alphabet for DNA and RNA:
The work builds off of previous work, which had expanded the genetic alphabet to six letters. The researchers call their eight-lettered nucleic acids "hachimoji,"...
Homework Statement
A molecule of DNA (deoxyribonucleic acid) is 2.10 μm long. The ends of the molecule become singly ionized: negative on one end, positive on the other. The helical molecule acts like a spring and compresses 1.09% upon becoming charged. Determine the effective spring constant...
I have read many sources on DNA and still have a few questions. Let me start with this one, and depending on the answers I will ask more.
Question 1. f I were to look into a human cell how would I see the DNA? Is there a single very long copy of the DNA string or are there two copies.
Question...
Paternal transmission of mitochondrial DNA (mtDNA) may be possible, a new study suggests – contradicting the accepted view that it is passed on exclusively through maternal inheritance.
The find, made by a team led by Taosheng Huang from Cincinnati Children’s Hospital Medical Centre, and...
Homework Statement
The Reason for the Double helical Structure of DNA is the operation of -
A) Van Der Waals Forces
B)Dipole Dipole Interactions
C)Hydrogen Bonding
D)Electrostatic Attraction
2. Background of question
This question ,is part into the home work asignment my chem tracher...
As we know, both strands in DNA is complementary to each other, it means that nucleotide sequence in one strand completely defines the sequence in the second strand.
Bacteria has got one, circular chromosome and it contains (almost) only genes. So if there are 100 genes in one strand then...
Does the human DNA contain information that could, combined with other data, tell what kinds of chemicals will their digestive system process or not? For instance, there are people that have hereditary fructose intolerance (not to be confused with fructose malabsorption).
Is such a lack of an...
@Ygggdrasil is far more qualified to comment on this than I am, but it seems like a good idea to raise the issue. Published today July 16, 2018 Letter in Nature Biotechnology:
https://www.nature.com/articles/Nbt.4192
M. Kosicki, K. Tomberg & A Bradley
Abstract:
In plain English this says...
Very short and general precis: Analyzing the 'barcode' gene in mitochondria (big data source) has found that most current animal species have comparatively tiny genetic diversity, humans included. Based on the data, the conclusion is modern human genetic diversity is low, and modern humans as a...
Question
Form the canoncial partition using the following conditions:
2 N-particles long strands can join each other at the i-th particle to form a double helix chain.
Otherwise, the i-th particle of each strand can also be left unattached, leaving the chain "open"
An "open" link gives the...
https://qph.ec.quoracdn.net/main-qimg-409fb82646033d7d8ca89fc5ec6401b2-c
Its behavior is not wolflike at all... How is this compatible with the DNA structure which is extremely wolf-like? Even Akita and Alaskan malamutes were less wolfy, even though they were in the top 4 - 1. Shiba 2. Chow...