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The Galilean realization of the special principle of relativity (indistinguishability of inertial frames) is simply observed to be inaccurate and the Lorentzian/Minkowskian realization is closer to the observed phenomena. Within GR it's even refined to be valid only locally, and that's the hitherto most comprehensive spacetime model, which is consistent with all observations, and there are some very accurate ones (pulsar timing, gravitational wave shapes, motion of stars around the black hole in our galaxy,...) in favor of GR (e.g., when tested against post-Newtonian parametrizations).