COVID-19 Coronavirus Containment Efforts

In summary, the Centers for Disease Control and Prevention (CDC) is closely monitoring an outbreak of respiratory illness caused by a novel (new) Coronavirus named 2019-nCoV. Cases have been identified in a growing number of other locations, including the United States. CDC will update the following U.S. map daily. Information regarding the number of people under investigation will be updated regularly on Mondays, Wednesdays, and Fridays.
  • #3,396
What's your thought about the 14-day Covid-19 symptom-based test to clear persons to return to work?
 
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  • #3,397
Vanadium 50 said:
The statement was
anorlunda said:
the assertion that the Coronavirus caused deaths in April that would have occurred in June is not correct.
The statement clearly refers to the majority of deaths. We also had someone saying "people who would have died in June died in April" or something like that earlier in this thread. To make that true the numbers would need to match, or at least be similar. They are not. COVID-19 killed many people who would have lived on for much longer than June.
 
  • #3,398
I can only go by what is written. That's what was written. You seem to have the ability to read minds, although I don't think you are doing a very good job of it with me.
 
  • #3,399
weird

I posted/quoted an article on the possible treatment of COVID via radiation therapy that seemed exciting news...it got deleted because it said unproven treatments shouldn't be posted.

The entire point of the article was that it was a possible treatment being tested and studied with promising early results. How is that different from every other article people post on possible new treatments/vaccines that are ALL UNPROVEN? Everything is unproven at this point!

My article (and my previous ones) and everyone else's all say these are simply exciting new possibilities with good early results...are we suddenly not allowed to report such news? I better see every other person's posts of such nature deleted in this thread in the future.
 
  • #3,400
So, is the policy that we cannot post on today's reports on dexamethasone?

It's not a proven drug either. Although, every news outlet is reporting on it?
 
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  • #3,401
kyphysics said:
So, is the policy that we cannot post on today's reports on dexamethasone?

It's not a proven drug either. Although, every news outlet is reporting on it?
Apparently, it is proven now according to the New York Times;

An inexpensive drug reduces virus deaths, scientists say.
Scientists at the University of Oxford said on Tuesday that they have identified what they called the first drug proven to reduce coronavirus-related deaths, after a 6,000-patient trial of the drug in Britain showed that a low-cost steroid could reduce deaths significantly for hospitalized patients.

The steroid, dexamethasone, reduced deaths by a third in patients receiving ventilation, and by a fifth in patients receiving only oxygen treatment, the scientists said. They found no benefit from the drug in patients who did not need respiratory support.

Matt Hancock, Britain’s health secretary, said National Health Service doctors would begin treating patients with the drug on Tuesday afternoon.

The government started stockpiling dexamethasone several months ago because it was hopeful about the potential of the drug, Mr. Hancock said, and now has 200,000 doses on hand.
 
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  • #3,402
bob012345 said:
The steroid, dexamethasone, reduced deaths by a third in patients receiving ventilation, and by a fifth in patients receiving only oxygen treatment, the scientists said. They found no benefit from the drug in patients who did not need respiratory support.
Not beneficial to those not using oxygen or ventilation.
 
  • #3,403
kadiot said:
Not beneficial to those not using oxygen or ventilation.
These are also less likely to die.

We had a thread about low-dose ionizing radiation. I don't know if it's still there, but we certainly had a thread about it.
Vanadium 50 said:
I can only go by what is written. That's what was written. You seem to have the ability to read minds, although I don't think you are doing a very good job of it with me.
What was written was not explicitly either interpretation, but one interpretation is obviously silly. You picked that one to argue against.
 
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  • #3,404
anorlunda said:
This is a very emotional story about deaths in a nursing home. Despite forewarning, and despite believing that they were fully prepared, the virus got into this nursing home and killed 21 residents in a short time...

But the article says that the average stay for residents of that home is 3 years, and one of the victims was there for 15 years. Therefore, the assertion that the Coronavirus caused deaths in April that would have occurred in June is not correct.
The article says there were 112 residents, of which an estimated 80 were infected. This is consistent with the fraction infected if everyone is exposed, that we've seen elsewhere (70%).

An average length of stay of three years is 3.1 deaths per month, or 9 in a typical 3-month period. And since COVID-19 preys on the weakest, I think it is quite plausible that roughly 9 of those 21 killed were likely to die between April and June with or without the virus.

Of course, what they haven't said is if there were additional deaths not resulting from COVID-19 in April, though with 70% infected, 1 additional death not COVID-related would be statistically predicted.

Also, while a resident who has been there 15 years clearly proved him/herself unusually hardy, they also were running on borrowed time. It's unlikely that someone who arrived 15 years ago unusually hardy is still unusually hardy 15 years later.
Therefore, victims could not be saved by use of ventilators. That fact, rather than the preexisting state of health of the residents could account for the very high mortality rate.
It's certainly likely to have contributed, but in order to decline a ventilator you first have to be sick enough to need one. In addition, the ventilator survival rate has been reported to be quite poor (and again, probably gets worse with underlying health issues). A nursing home is a place where by definition everyone is in poor health, with the potential exception of people who voluntarily go to be with a spouse (though that would be financially burdensome and awkward).
 
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  • #3,405
bob012345 said:
Also factor in increased and expanded testing rates at least in Texas.
More testing would certainly lead to an increase in 'confirmed' cases of COVID-19, especially where testing has been limited. On the other hand, those of are positive cases. Perhaps more relevant is the number of hospitalizations.

CBS News and other media report an increase in hospitalizations in Texas. "The state's Department of Health and Human Services reported 2,326 lab-confirmed COVID-19 patients who are currently in Texas hospitals, bypassing the previous record high on Sunday of 2,287. There are currently 51,365 total staffed hospital beds in the state, with 14,525 hospital beds available. Only 1,626 beds in Intensive Care Units are currently available in the state." On Saturday, there were 2242 hospitalizations. The numbers represent cumulative values as opposed to new one day incremental values.

https://www.cbsnews.com/news/texas-coronavirus-highest-day-hospitalized-patients/
https://www.tmc.edu/coronavirus-updates/tmc-daily-new-covid-19-hospitalizations/
https://www.tmc.edu/coronavirus-updates/infection-rate-in-the-greater-houston-area/

The Texas Medical Center publishes COVID-19 data for the Houston area (includes Harris Counties and probably surrounding counties for folks treated in Houston). There are other regions like Dallas, Fort Worth, Austin, San Antonio, that are also seeing increases.

https://txdshs.maps.arcgis.com/apps/opsdashboard/index.html#/0d8bdf9be927459d9cb11b9eaef6101f

As of June 16, Texas Department of State Health Services reports 2518 hospitalizations. There are 54844 staffed hospital beds, 14993 hospital beds available, 1675 ICU beds available, and 5869 ventilators available.
 
  • #3,406
kyphysics said:
So, is the policy that we cannot post on today's reports on dexamethasone?

It's not a proven drug either. Although, every news outlet is reporting on it?
bob012345 said:
Apparently, it is proven now according to the New York Times;

An inexpensive drug reduces virus deaths, scientists say.
Scientists at the University of Oxford said on Tuesday that they have identified what they called the first drug proven to reduce coronavirus-related deaths, after a 6,000-patient trial of the drug in Britain showed that a low-cost steroid could reduce deaths significantly for hospitalized patients.

The steroid, dexamethasone, reduced deaths by a third in patients receiving ventilation, and by a fifth in patients receiving only oxygen treatment, the scientists said. They found no benefit from the drug in patients who did not need respiratory support.

Matt Hancock, Britain’s health secretary, said National Health Service doctors would begin treating patients with the drug on Tuesday afternoon.

The government started stockpiling dexamethasone several months ago because it was hopeful about the potential of the drug, Mr. Hancock said, and now has 200,000 doses on hand.

Interesting reports. The cytokine storm hypothesis for COVID-19 is roughly that there is "too much inflammation". It was also a hypothesized caused of death for the 1918 influenza pandemic and SARS. It is natural to try an anti-inflammatory which could be a (cortico)steroid like dexamathasone, or a non-steroid (NSAID) like Ibuprufen. However, inflammation is also part of the immune response, and may help to clear the virus from the body. Earlier studies on SARS suggested that such treatments did not have a positive effect on mortality, and slowed clearance of the virus. So there has been much discussion whether, when and how to give such drugs in COVID-19.

https://www.bbc.com/future/article/20200505-cytokine-storms-when-the-body-attacks-itself: "The solution, then, might be to quiet the rampaging immune response. Steroids are often the first choice of treatment. They act broadly to dampen the immune system – but, of course, that system is needed at a lower intensity to fight invaders. In the case of Covid-19, it’s not yet clear if steroids are beneficial or harmful, Cron says."
https://edition.cnn.com/2020/03/16/...ench-health-minister-scn-intl-scli/index.html
https://www.frontiersin.org/articles/10.3389/fmed.2020.00170/full
https://www.nature.com/articles/s41375-020-0848-3
https://erj.ersjournals.com/content/early/2020/04/20/13993003.01009-2020
 
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  • #3,407
russ_watters said:
In addition, the ventilator survival rate has been reported to be quite poor (and again, probably gets worse with underlying health issues).

This estimate may be changing. The ventilator survival rates may have been low because healthcare systems were overwhelmed, and not able to optimize ventilator treatment for each patient. It may also be that doctors now know who is likely to benefit from ventilator treatment, and may be choosing patients differently now than earlier. It could also be that the early numbers were incomplete. https://www.npr.org/sections/health-shots/2020/05/15/856768020/new-evidence-suggests-covid-19-patients-on-ventilators-usually-survive

There is a similar pattern for ECMO. Early numbers indicated more than 90% mortality, but current estimates from ongoing studies suggest a survival rate of 50%. See Graeme MacLaren's comments around 32:00-33:30 in Managing the critically ill COVID-19 patient: From oxygen to ECMO.
 
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  • #3,408
I was surprised to find (where I am) that mask requirements have been lifted while we transition to reopening. I don't know what people are thinking. If we had been wearing masks since the start, we probably wouldn't have needed to shutdown in the first place, and many thousands of deaths may have been prevenable.

Also, recently Fauci finally admitted to lying about the effectiveness of masks and explained why they launched their misinformation campaign.
 
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  • #3,409
Jarvis323 said:
Also, recently Fauci finally admitted to lying about the effectiveness of masks and explained why they launched their misinformation campaign. In my opinion, this should be a career ending scandal for everyone involved.
Do you have a source for that?
 
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  • #3,411
What is dexamethasone?

Dexamethasone is a type of medication called a corticosteroid that has numerous effects on the human body.
The major effect of dexamethasone on COVID-19 is that it can help calm down the uncontrolled inflammation that occurs in severely-ill COVID-19 patients.

In patients who only have mild disease, dexamethasone doesn't seem to have any beneficial effect.

Dexamethasone has NO clinically significant antiviral properties and can actually suppress the immune response, potentially increasing your risk of viral, bacterial, and fungal infection, INCLUDING COVID-19.

Powerful corticosteroids like dexamethasone can have severe and life-threatening side effects and should only be taken under the supervision of a properly licensed physician. It should only be taken when the potential benefit outweighs the risk of using the drug. It should also be used at the correct dosage and duration or it will not have the desired effect. Please don't experiment with dexamethasone. It can do a lot more harm than good if improperly used.
 
  • #3,413
mfb said:
That doesn't back your claims.

Globally, recorded recoveries are now nearly half of all confirmed cases, but the daily new cases are still going up. 120,000 now. We'll reach 10 million confirmed cases in early July at that rate.

I apologize if I come off as brash. I understand that the campaign to discourage mask use could be framed in a more polite way, but I honestly think my framing of the incident as a misinformation campaign is quite accurate from a technical standpoint. I also realize that they had a "noble" motivation to lie to us, which is what Fauci explains in the video. I suppose it is up for debate whether scientists and government officials should lie to the public when they think the ends justify the means. In my opinion, it causes irreparable damage to the scientific community, our government institutions, and society in general. Many people won't trust the government, or scientific authorities in the future about other topics. And why should they if disinformation has become a normalized practice/strategy?

In terms of whether mask use could have prevented thousands of deaths and the need for a lock down, you can't prove anything about that. But I challenge you to compare countries which instituted mandatory mask use early on to those that didn't.

If we are being honest, the misinformation campaign, late adoption of the use of masks as a strategy (along with unpreparedness/empty stockpiles), is turning out to look very much like a disastrous set of mistakes.

I'm sorry I am being so pessimistic, instead of following suit to brush this all under the rug. It has been very frustrating being lied to (or at the very least being assertively told things were true, that were at best uncertain at the time, but turned out to be false) constantly throughout this whole thing. Now it seems that most people are just confused, hanging on to all kinds of false assumptions, spreading misinformation on social media, and in general being very distrustful of everything else they are being told. So now we are asked to swallow the fact that we were lied to, because it was for our own good. Ok, thanks for lying to us, I guess.
 
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  • #3,414
Jarvis323 said:
I apologize if I come off as brash. I understand that the campaign to discourage mask use could be framed in a more polite way, but I honestly think my framing of the incident as a misinformation campaign is quite accurate from a technical standpoint. I also realize that they had a "noble" motivation to lie to us, which is what Fauci explains in the video. I suppose it is up for debate whether scientists and government officials should lie to the public when they think the ends justify the means. In my opinion, it causes irreparable damage to the scientific community, our government institutions, and society in general. Many people won't trust the government, or scientific authorities in the future about other topics. And why should they if disinformation has become a normalized practice/strategy?

In terms of whether mask use could have prevented thousands of deaths and the need for a lock down, you can't prove anything about that. But I challenge you to compare countries which instituted mandatory mask use early on to those that didn't.

If we are being honest, the misinformation campaign, late adoption of the use of masks as a strategy (along with unpreparedness/empty stockpiles), is turning out to look very much like a disastrous set of mistakes.

I'm sorry I am being so pessimistic, instead of following suit to brush this all under the rug. It has been very frustrating being lied to (or at the very least being assertively told things were true, that were at best uncertain at the time, but turned out to be false) constantly throughout this whole thing. My intelligence has been constantly insulted. But it's not just me, it's the public they are talking to. So I guess they think the public is dumb, and us intellectuals need to just cover our eyes or something. Now it seems that most people are just confused, hanging on to all kinds of false assumptions, spreading misinformation on social media, and in general being very distrustful of everything else they are being told. So now we are asked to swallow the fact that we were lied to, because it was for our own good. Ok, thanks for lying to us, I guess.

I agree that much public messaging on masks was misleading (you can see earlier in this thread there was vigorous discussion, eg. between @bhobba and @chemisttree). However, it doesn't mean that the public health recommendations were wrong, but that their rationale was poorly explained, eroding trust. Overall, the issue was quite controversial among experts (George Gao, a Chinese expert thought it was important, and major medical journals like the New England Journal of Medicine, Lancet, and BMJ took quite different positions). In the US, the CDC still does not recommend community wearing of surgical masks (there is good evidence that these protect the wearer), but instead suggests cloth masks (there is weaker evidence about their ability to protect the wearer or others).

Incidentally, the experience of New Zealand does suggest that in some contexts (in which other measures are taken), community mask wearing is not necessary for achieving an excellent outcome. https://www.health.govt.nz/our-work...eral-public/covid-19-use-face-masks-community
 
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  • #3,415
atyy said:
but that their rationale was poorly explained, eroding trust.
This is a polite way of saying they lied. It sounds nicer, but it's less clear. But also, it wasn't just a random lie, it was a coordinated disinformation campaign. We can talk about it in all sorts of indirect ways without admitting it, but it's pretty obvious anyway by now, so what's the point?
 
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  • #3,416
https://www.factcheck.org/2020/05/outdated-fauci-video-on-face-masks-shared-out-of-context/

Dr Fauci (March 8), "There’s no reason to be walking around with a mask." hat's an unfortunate mis-statement. Of the reason to wear a mask, in public, is to mitigate spread of an airborne virus responsible for a respiratory illness. It's the same reason that one wears a mask when one has a cold or influenza, although many people do not. When I thought I had influenza (fever and cough), when I arrived at the clinic, I immediately put on a mask, which I retrieved from a dispenser near the main entry.

I use the mask when cycling in smoky (from wildfires) or dusty (fine volcanic ash and desert sand) conditions in order to prevent (or mitigate) inhalation of smoke or dust particulates (< 2.5 microns). It works.

Fauci's comment was made because there was not enough masks available to the population, and he felt that doctors, nurses and other health care workers needed masks more than the general public. The 'stay-at-home' orders were necessary, because there were not enough masks to go around. At about the time states started implementing 'stay-at-home', we saw folks going on buying sprees and hoarding supplies of toilet paper, paper towels, alcohol, sanitizers and so on. The limited supply of masks went to those who got there first, such that many went without, and folks started buying online in competition with the health industry and state/local governments. Those in greatest need often went without. My wife order a package of masks in late March, and we did not receive the order until mid May (~8 weeks later).

I had to wear a bandana, then a handmade clothe face mask until we received the proper masks. Actually, a bandana or clothe mask with 3-4 layers of coffee filter would be effective. I confirmed with a family member who is a doctor and who treats patients with a variety of respiratory infections, including SARS-CoV-2.
 
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  • #3,417
atyy said:
I agree that much public messaging on masks was misleading (you can see earlier in this thread there was vigorous discussion, eg. between @bhobba and @chemisttree). However, it doesn't mean that the public health recommendations were wrong, but that their rationale was poorly explained, eroding trust.

Yes knowledge of this virus has moved on since those early posts. It is now known it can take a while for symptoms to show and you are infectious then:
https://theconversation.com/masks-h...q3bFQiLa7Pj1S3Be8145QyTC2buRb9ak6hvCoTWaUX_co

But remember in places like Australia infections are so low, those that have it are vastly coming from overseas and quarantined. We had 18 new cases today - but it was reported virtually all was from people quarantined from overseas. Local transmission is very very low - in Queensland just one today and we are getting more and more days with 0 cases. Only 5 active cases. In such a situation the optional wearing of masks, which is the rule here, is reasonable. Should a second wave strike, or we have local outbreaks then yes - masks should, and with what we now know would, be mandatory.

Thanks
Bill
 
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  • #3,418
bhobba said:
Yes knowledge of this virus has moved on since those early posts. It is now known it can take a while for symptoms to show and you are infectious then:
https://theconversation.com/masks-h...q3bFQiLa7Pj1S3Be8145QyTC2buRb9ak6hvCoTWaUX_co

But remember in places like Australia infections are so low, those that have it are vastly coming from overseas and quarantined. We had 18 new cases today - but it was reported virtually all was from people quarantined from overseas. Local transmission is very very low - in Queensland just one today and we are getting more and more days with 0 cases. Only 5 active cases. In such a situation the optional wearing of masks, which is the rule here, is reasonable. Should a second wave strike, or we have local outbreaks then yes - masks should, and with what we now know would, be mandatory.

Thanks
Bill
There is no shame in having trusted public health officials.

But the, "we now know that", excuse falls short. The disinformation went above and beyond, to the point that people were convinced mask use was actually dangerous and worse than nothing. At that time in the US, people were being ridiculed and even in some cases attacked for being seen wearing masks in public, even cloth ones.

To make things worse, the denial of asymptomatic spread was actually pretty dubious at the time. It was't proven, but we had evidence of asymptomatic spread very early on. The late official acknowledgment of that wasn't the reason the truth changed about the danger, effectiveness, and advanced training required for masks to do more good than harm.

Why they were so dismissive of asymptomatic spread for so long is another issue. I suspect they were trying to avoid scaring people and at that time were likely worried about the impact on the economy. It was unproven at the time, but rather than saying that some evidence suggests asymptomatic spreading, but we're not sure, they chose to reassure us that asymptomatic spreading wasn't a concern. At the time they were convincing us that masks are dangerous, even if they weren't ready to warn us about asymptomatic spreading, they should have at least been concerned about it privately.

At that time it was all about hand washing. And they had also dismissed evidence of spreading through aerosols.
 
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  • #3,419
It was obvious to me when Fauci was discouraging mask use it was to preserve the supply for the medical workers. So, I don't feel like I was "lied to" at all.

And when he said general public use of mask was a waste, I saw that as truth - after seeing people out in public with masks on, reaching up to scratch their noses under the mask. Or wearing the mask upside down. Or having their nose sticking out above the mask.
 
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  • #3,420
Jarvis323 said:
The disinformation went above and beyond, to the point that people were convinced mask use was actually dangerous and worse than nothing.

If not needed it can make the situation worse because, as articles at the time explained, many people find them 'itchy' and scratch their face, which is a known method of transmission. It is a balance between benefit and risk. I am one of those people that even without a mask scratches their face, it's almost involuntary. With a mask it would likely be worse. If mask wearing was made compulsory, I would personally go out even less frequently (which now is on the average about once every two days and then only for short periods of time) than I do now, with a hand sanitizer in my pocket to be used frequently to avoid issues with scratching my face.

Thanks
Bill
 
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  • #3,421
bhobba said:
If not needed it can make the situation worse because, as articles at the time explained, many people find them 'itchy' and scratch their face, which is a known method of transmission. It is a balance between benefit and risk. I am one of those people that even without a mask scratches their face, it's almost involuntary. With a mask it would likely be worse. If mask wearing was made compulsory, I would personally go out even less frequently (which now is on the average about once every two days and then only for short periods of time) than I do now, with a hand sanitizer in my pocket to be used frequently to avoid issues with scratching my face.

Thanks
Bill
That's a fair point.
 
  • #3,422
bhobba said:
If mask wearing was made compulsory, I would personally go out even less frequently (which now is on the average about once every two days and then only for short periods of time) than I do now, with a hand sanitizer in my pocket to be used frequently to avoid issues with scratching my face.
Wearing a mask in public in NY state is compulsory in most areas, but many folks ignore it. In Washington state, it seems to be voluntary, but too many folks ignore.

When I go out in public, I wear a mask. I carry hand sanitizer. If I adjust the mask, I'll use the hand sanitizer on my hands before I touch anything else. When I return to my personal vehicle, I remove the mask and use hand sanitizer. I also observe the recommended social distancing to the extent possible. When I return home, I wash my hands with soap and water, then apply hand sanitizer.

Since I have limited masks, I reuse them, but I wash them in alcohol.
 
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  • #3,423
gmax137 said:
It was obvious to me when Fauci was discouraging mask use it was to preserve the supply for the medical workers. So, I don't feel like I was "lied to" at all.

And when he said general public use of mask was a waste, I saw that as truth - after seeing people out in public with masks on, reaching up to scratch their noses under the mask. Or wearing the mask upside down. Or having their nose sticking out above the mask.
I think officials also didn't realize the extent the virus had already spread among the population. So if they were working with the assumptions that almost everyone was free of the virus and that asymptomatic transmission was unlikely, the risk of catching it from some random person was low. Fauci implied this belief when he said, "The masks are important for someone who’s infected to prevent them from infecting someone else… Right now in the United States, people should not be walking around with masks." When it became clear that asymptomatic and pre-symptomatic transmission was a factor, it changed the equation. There were likely a lot more people walking around infected and spreading the virus. It made sense to revise the guidance about masks.
 
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  • #3,424
Jarvis323 said:
To make things worse, the denial of asymptomatic spread was actually pretty dubious at the time. It was't proven, but we had evidence of asymptomatic spread very early on. The late official acknowledgment of that wasn't the reason the truth changed about the danger, effectiveness, and advanced training required for masks to do more good than harm.

Why they were so dismissive of asymptomatic spread for so long is another issue. I suspect they were trying to avoid scaring people and at that time were likely worried about the impact on the economy. It was unproven at the time, but rather than saying that some evidence suggests asymptomatic spreading, but we're not sure, they chose to reassure us that asymptomatic spreading wasn't a concern. At the time they were convincing us that masks are dangerous, even if they weren't ready to warn us about asymptomatic spreading, they should have at least been concerned about it privately.

The possibility of asymptomatic spread was discussed early on and uncertainties were acknowledged in the WHO report on China. The early thoughts were not that there was no asymptomatic spread, rather that it played a small role in overall transmission, and thus measures like symptomatic people self-isolating before testing, quarantine of positive symptomatic cases, and hand washing and social distancing in the community would be able to manage the spread of the disease. It is still not clear whether this is incorrect (recent comments by Fauci indicates he thinks this is now wrong, whereas the WHO's recent comments indicate the evidence available to them is still consistent with this earlier view - it is important to note that the uncertainties were expressed in the original WHO comments, and it has not "backtracked").

Jarvis323 said:
At that time it was all about hand washing. And they had also dismissed evidence of spreading through aerosols.

It is still thought not to spread through aerosols except in certain situations in hospital procedures. Based on the choir incident, it had been suggested otherwise. However, that incident is still consistent with being driven by symptomatic spread and droplet transmission (lack of social distancing, enhanced spread of droplets by singing).
 
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  • #3,425
From what I understand a vaccine is supposed to stimulate your immune system to create antibodies to fight off the real virus.

But this concerns me. What if the immunity produced by the human body is not enough to completely eliminate all the Covid-19 symptoms for a significant amount of time?

If a vaccine is developed and approved and this is the result, then what?
 
  • #3,426
kolleamm said:
From what I understand a vaccine is supposed to stimulate your immune system to create antibodies to fight off the real virus.

But this concerns me. What if the immunity produced by the human body is not enough to completely eliminate all the Covid-19 symptoms for a significant amount of time?

If a vaccine is developed and approved and this is the result, then what?

This is what a Phase III clinical trial is supposed to determine. A large group of at risk people will be randomized to either receive the vaccine or a placebo. Scientists will then track the groups to see how many in each group contract the disease, show symptoms, and the outcome of those symptoms. A properly run clinical trial would likely be able to identify a vaccine that does not provide effective protection from the virus.
 
  • #3,427
https://news.yahoo.com/covid-19-now-believed-attack-052400255.html
New York Gov. Andrew Cuomo (D) said Sunday that three New York children have died and 73 have become gravely ill with an inflammatory disease tied to COVID-19. The illness, pediatric multisystem inflammatory syndrome, has symptoms similar to toxic shock or Kawasaki disease. Two of the children who died were of elementary school age, the third was an adolescent, and they were from three separate counties and had no known underlying health issues, said New York health commissioner Dr. Howard Zucker. Cases have been reported in several other states.
It isn't just children struggling with arterial inflammation. In fact, for a virus originally believed to primarily destroy the lungs, COVID-19 also "attacks the heart, weakening its muscles and disrupting its critical rhythm," the Post reports. "It savages kidneys so badly some hospitals have run short of dialysis equipment. It crawls along the nervous system, destroying taste and smell and occasionally reaching the brain. It creates blood clots that can kill with sudden efficiency."

236 people got the Coronavirus after an Oregon church held services during lockdown
https://news.yahoo.com/236-people-got-coronavirus-oregon-000100604.html

60% of attendees were infected

Gatherings may become superspreading events.

https://news.yahoo.com/group-12-friends-test-positive-151901918.html
https://www.cnn.com/2020/06/17/us/group-tests-positive-florida-bar/index.html

What made Blaine County Idaho’s Coronavirus hot spot? Wealthy visitors and recreation

https://www.idahostatesman.com/news/coronavirus/article241448211.html
. . . thousands of skiers, outdoors enthusiasts and wealthy part-time residents with homes in New York, Seattle and Los Angeles flood the valley. From December to March, roughly 30,000 people from around the world usually land at the Friedman Memorial Airport in Hailey and visit restaurants, ski slopes and resorts.
Outsiders bring communicable diseases to remote areas.

February 21, 2020 - Presumed Asymptomatic Carrier Transmission of COVID-19
https://jamanetwork.com/journals/jama/fullarticle/2762028
 
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atyy said:
The possibility of asymptomatic spread was discussed early on and uncertainties were acknowledged in the WHO report on China. The early thoughts were not that there was no asymptomatic spread, rather that it played a small role in overall transmission, and thus measures like symptomatic people self-isolating before testing, quarantine of positive symptomatic cases, and hand washing and social distancing in the community would be able to manage the spread of the disease. It is still not clear whether this is incorrect (recent comments by Fauci indicates he thinks this is now wrong, whereas the WHO's recent comments indicate the evidence available to them is still consistent with this earlier view - it is important to note that the uncertainties were expressed in the original WHO comments, and it has not "backtracked").

This is another example. If you watch the full video, it is obvious her agenda was to advocate for a contact tracing program to track symptomatic people. That in of itself is reasonable. But she seemed to throw in a lie (if it isn't a lie they're out of touch) at the end about the evidence of asymptomatic spread as an extra argument to support their position. They didn't really need to. But it has become normalized by now.

The same thing with the masks. They were in a situation where they felt they needed to advocate for the public to not wear masks at the time. So they made their case, including an appeal to altruism, but threw in some disinformation for good measure.

Aerosol transmission was a big issue while guidelines were made for medical workers. Nurses were banned from using N95's except in specific procedures. The reason was obviously that their were shortages. So they decided to change the official guidelines, to discourage or block nurses and doctors from being able to wear them while handling Covid-19 patients. In support of that recommendation, they also stated an official thought about aerosol transmission. And that thought was not evidence based. Nurses were protesting and some quitting.

And that was really mind bending, because while they had been telling nurses that N95's aren't necessary and surgical masks were good enough, they were telling the public only N95's offered protection and surgical masks increased their risk.
 
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Ygggdrasil said:
This is what a Phase III clinical trial is supposed to determine. A large group of at risk people will be randomized to either receive the vaccine or a placebo. Scientists will then track the groups to see how many in each group contract the disease, show symptoms, and the outcome of those symptoms. A properly run clinical trial would likely be able to identify a vaccine that does not provide effective protection from the virus.
Wouldn't all vaccines provide the same amount of protection? Aren't the clinical trials just to determine they are safe to use?
 
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kolleamm said:
If a vaccine is developed and approved and this is the result, then what?

I will do a separate post on the state of play with vaccines.

Thanks
Bill
 
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